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CAS No 101-26-8 , (1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate Search by region : France

  • Name: (1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate
  • Synonyms: Regonol;bromide;Mestinon; Kalimin; 101-26-8; Kalymin; Regonal;(1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate; Mestinon bromide; 3-(Dimethylcarbamoyloxy)-1-methylpyridinium Bromide;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 2
  • Melting Point: 154 °C
  • Boiling Point: 88 (25 torr)
  • Density: 0.9613 g/cm3 (20 C)
  • Refractive index: 1.48 (20 C)
  • Water Solubility: soluble in ethanol and water
  • Safety Statements: 22-36/37/39-45
  • Hazard Symbols: T+: Very toxic;
  • EINECS: 202-929-9
  • Molecular Weight: 261.11572
  • InchiKey: VNYBTNPBYXSMOO-UHFFFAOYSA-M
  • InChI: InChI=1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,
    1-3H3;1H/q+1;/p-1
  • Risk Statements: 26/27/28-43
  • Molecular Formula: C9H13BrN2O2
  • Molecular Structure:CAS No:101-26-8 (1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate

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101-26-8 PYRIDOSTIGMINE BROMIDE

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References of (1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate
Title: Pyridostigmine Bromide
CAS Registry Number: 101-26-8
CAS Name: 3-[[(Dimethylamino)carbonyl]oxy]-1-methylpyridinium bromide
Synonyms: 3-hydroxy-1-methylpyridinium bromide dimethylcarbamate; 1-methyl-3-hydroxypyridinium bromide dimethylcarbamate; 3-(dimethylcarbamyloxy)-1-methylpyridinium bromide
Manufacturers' Codes: Ro-1-5130
Trademarks: Kalymin (Temmler); Mestinon (Roche); Regonol (Organon)
Molecular Formula: C9H13BrN2O2
Molecular Weight: 261.12
Percent Composition: C 41.40%, H 5.02%, Br 30.60%, N 10.73%, O 12.25%
Literature References: Reversible inhibitor of acetylcholinesterase. Prepn: Urban, US 2572579 (1951 to Hoffmann-La Roche). Mechanism of protective effect in soman poisoning: X. Deyi et al., Fundam. Appl. Toxicol. 1, 217 (1981). Evaluation of effect on neuromuscular function: M. Glikson et al., ibid. 16, 288 (1991). Evaluation of side effects profile under desert conditions: J. E. Cook et al., Mil. Med. 157, 250 (1992). Review of prophylactic effect in nerve agent poisoning: R. M. Dawson, J. Appl. Toxicol. 14, 317 (1994).
Properties: Shiny, hygroscopic crystals from abs ethanol, mp 152-154°. Freely sol in water, alcohol. Practically insol in ether, acetone, benzene. Aq solns may be sterilized by autoclaving with steam.
Melting point: mp 152-154°
Therap-Cat: Cholinergic; in treatment of myasthenia gravis. Pre-exposure antidote to chemical warfare agents.
Keywords: Cholinergic.