Home > Name List By other > (-)-Huperzine A

CAS No 102518-79-6 , (-)-Huperzine A

  • Name: (-)-Huperzine A
  • Synonyms: HUPERAZINE A(SH);(-)-Huperzine A; Selagine;(-)-Selagine; (-) Huperzine A;(+-)-huperzine A;
  • CAS Registry Number:
  • Transport: UN 1544 6.1/PG 2
  • Melting Point: 211-216oC
  • Density: 1.2 g/cm3
  • Refractive index: 1.626
  • Safety Statements: R26/27/28;R36/37/38
  • Hazard Symbols: T+: Very toxic;
  • Molecular Weight: 242.32
  • InChI: InChI=1/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
  • Risk Statements: S26;S36/37/39;S45
  • Molecular Formula: C15H18N2O
  • Molecular Structure:CAS No:102518-79-6 (-)-Huperzine A

Related products

Search by region :

Select to

102518-79-6 HUPERZINE A 1%

  • United States Aceto Corp. [Manufacturer]
  • Tel: 516-627-6000
  • Fax: 516-627-6093
  • Address: One Hollow Lane
    Lake Success, NY 11042-1215 null,nullUnited States
Contact Supplier

102518-79-6 HUPERAZINE A(SH)

  • HUPERAZINE A(SH)Selagine
  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 null,nullUnited States
Contact Supplier

102518-79-6 Huperzine-A

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
Contact Supplier

102518-79-6 Huperzine A

  • Huperzine A (+-)-Huperzine A HUPERAZINE A(SH) Selagine (-) Huperzine A Huperzine-A (-)-HUPERZINE A (+-)HUPERZINE A huperzine (-)Huperzine A
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
Contact Supplier

102518-79-6 HUPERZINE A

  • United States NetQem, LLC [Manufacturer]
  • Tel: (919) 544-4122
  • Fax: (919) 544-4109
  • Address: NetQem, LLC
    P.O. Box 12091
    Research Triangle Park
    NC 27709, USA null,nullUnited States
Contact Supplier

102518-79-6 HUPERZINE A

  • United States SYNASIA [Manufacturer]
  • Tel: 732-205-9880
  • Fax: 732-205-1788
  • Address: NJ Office:
    240 Amboy Avenue
    Metuchen NJ 08840 null,nullUnited States
Contact Supplier

102518-79-6 HUPERZINE-A

  • China NINGBO V&P CHEMISTRY [Manufacturer]
  • Tel: 86-574-27666767
  • Fax: 86-574-56704282
  • Address: 21/F, NO.11 BLDG,XIN TIAN DI,
    NO689, SHI JI ROAD,
    NINGBO,CHINA, 315040 null,nullChina
Contact Supplier

102518-79-6 (-)-HUPERZINE A, 99% HPLC

  • United States International Laboratory (IL) [Manufacturer]
  • Tel: 650-278-9963
  • Fax: 650-589-2786
  • Address: 1067 SNEATH LN
    SAN BRUNO
    CA 94066, USA null,nullUnited States
Contact Supplier

102518-79-6 HUPERZINE A

  • China SINO GREAT ENTERPRISE LTD. [Manufacturer]
  • Tel: +86-731-4427351
  • Fax: +86-731-4429615
  • Address: 154 Jianxiang South Road,
    Changsha, Hunan, China. null,nullChina
Contact Supplier

102518-79-6 Huperzine A

  • Huperzine ASelagine
  • China Hangzhou Pharma & Chem Co., Ltd. [Manufacturer]
  • Tel: +86 571 87040515
  • Fax: +86 571 87214761
  • Address: Hangzhou Pharma & Chem Co., Ltd.
    139 Qingchun Road, Hangzhou City,
    Zhejiang, China 310003 null,nullChina
Contact Supplier

Select to

2/15
Previous 1 2 3 4 5 6 7 8 9 10 Next
References of (-)-Huperzine A
Title: Huperzine A
CAS Registry Number: 102518-79-6
CAS Name: [5R-(5a,9b,11E)]-5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one
Synonyms: selagine; HUP
Molecular Formula: C15H18N2O
Molecular Weight: 242.32
Percent Composition: C 74.35%, H 7.49%, N 11.56%, O 6.60%
Literature References: Reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. Occurs as the (-)-form in the vegetative part of clubmosses; teas brewed from these mosses have traditionally been used in China to alleviate memory problems. Isolated as selagine from Lycopodium selago L., Lycopodiaceae: J. Muszynski, Q. J. Pharm. Pharmacol. 21, 34 (1948); from Huperzia serrata as huperzine: Chin. Co-op Res. Group, J. Tradit. Chin. Med. 2, 45 (1982). Original structure: Z. Valenta et al., Tetrahedron Lett. 1960, 26; revised structure as huperzine A: J.-S. Liu et al., Can. J. Chem. 64, 837 1986. Identity with selagine: W. A. Ayer et al., ibid. 67, 1538 (1989). Synthesis of (±)-form: A. P. Kozikowski et al., J. Org. Chem. 56, 4636 (1991); G. Campiani et al., ibid. 58, 7660 (1993). NMR spectra: B. N. Zhou et al., Phytochemistry 34, 1425 (1993). HPLC determn in serum: J. Ye et al., J. Chromatogr. B 817, 187 (2005). Anticholinesterase activity: Y.-E. Wang et al., Acta Pharmacol. Sin. 7, 110 (1986); binding profile of enantiomers: M. McKinney et al., Eur. J. Pharmacol. 203, 303 (1991); binding specificity: Y. Ashani et al., Mol. Pharmacol. 45, 555 (1994). Clinical evaluation in senile dementia: R.-W. Zhang et al., Acta Pharmacol. Sin. 12, 259 (1991). Brief review of chemistry and clinical use: D. Bai, Pure Appl. Chem. 65, 1103-1112 (1993).
Properties: Monoclinic crystals from acetone, mp 214-215°. [a]D -147° (c = 0.36 in CH3OH) (Ayer). Also reported as mp 230°. [a]D24.5 -150.4° (c = 0.498 in MeOH) (Liu). uv max (EtOH): 231, 313 nm (log e 4.01, 3.89).
Melting point: mp 214-215°; mp 230°
Optical Rotation: [a]D -147° (c = 0.36 in CH3OH) (Ayer); [a]D24.5 -150.4° (c = 0.498 in MeOH) (Liu)
Absorption maximum: uv max (EtOH): 231, 313 nm (log e 4.01, 3.89)
Therap-Cat: In treatment of memory disorders.