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CAS No 107254-86-4 , 5-nitro-2-(3-phenylpropylamino)benzoic acid Search by region : Germany

  • Name: 5-nitro-2-(3-phenylpropylamino)benzoic acid
  • Synonyms: 5-Nitro-2-(3-phenylpropylamino)benzoic acid; 107254-86-4; 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid;NPPB;5-nitro-2-(3-phenylpropylamino)benzoic acid;
  • CAS Registry Number:
  • Density: 1.323 g/cm3
  • Refractive index: 1.653
  • Water Solubility: Soluble in DMSO (50mg/ml) or 100% ethanol (3mg/ml); insoluble in water
  • Molecular Weight: 300.30924
  • InchiKey: WBSMIPAMAXNXFS-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-
    5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
  • Molecular Formula: C16H16N2O4
  • Molecular Structure:CAS No:107254-86-4 5-nitro-2-(3-phenylpropylamino)benzoic acid

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107254-86-4 NPPB

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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References of 5-nitro-2-(3-phenylpropylamino)benzoic acid
Title: NPPB
CAS Registry Number: 107254-86-4
CAS Name: 5-Nitro-2-[(3-phenylpropyl)amino]benzoic acid
Manufacturers' Codes: HOE-144
Molecular Formula: C16H16N2O4
Molecular Weight: 300.31
Percent Composition: C 63.99%, H 5.37%, N 9.33%, O 21.31%
Literature References: Inhibits efflux of ion channels; specificity is cell type dependent. Prepn: H. C. Englert et al., DE 3528048; eidem, US 4994493 (1987, 1991 both to Hoechst). Synthesis and characterization as potassium channel blocker: K. R. Giles et al., Bioorg. Med. Chem. Lett. 13, 293 (2003). Blocking kinetics of chloride channels: J. Dreinh?fer et al., Biochim. Biophys. Acta 946, 135 (1988). Effect on chloride ion transport: B. R. Branchini et al., Biochem. Biophys. Res. Commun. 176, 459 (1991); eidem, Arch. Biochem. Biophys. 318, 221 (1995); J.-A. Kim et al., Biochem. Biophys. Res. Commun. 309, 291 (2003).
Properties: Yellow crystals from isopropanol, mp 178-180°. Soly (mg/ml): 25 DMSO, 10 ethanol.
Melting point: mp 178-180°
Use: Biochemical probe primarily as a Cl- channel blocker.