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CAS No 11041-12-6 , Cholestyramine

  • Name: Cholestyramine
  • Synonyms: Cholybar;Cholestyraminechloride;Cholestyramine; Questran; Cuemid; Cholestyramine resin; Cholestyramine hydroxide;Colestyramin; LoCholest; Quantalan;Questran Light; Colestyramine; MK 135;
  • CAS Registry Number:
  • Safety Statements: Low toxicity by ingestion. Questionable human carcinogen producing colon tumors. An experimental teratogen. Other experimental reproductive effects. Toxic effects by ingestion: acidosis and nosebleeds. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 234-270-8
  • Molecular Weight: 385.66878
  • Molecular Formula: C27H47N

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11041-12-6 CHOLESTYRAMINE RESIN

  • CHOLESTYRAMINE RESIN Alias: cholestyraminechloride; colestyramin; polystyrenebenzyltrimethylaminoniumchloride CAS: 11041-12-6 EINECS: 234-270-8 M.F.: C27H47N M.W.: 385.66878 Description:White to buff-colored fine powder. Odorless or a slight amine od...
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11041-12-6 Colestyramine

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11041-12-6 cholestyramine

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References of Cholestyramine
Title: Cholestyramine Resin
CAS Registry Number: 11041-12-6
Synonyms: Colestyramin
Manufacturers' Codes: Dowex 1-X2-Cl; MK-135
Trademarks: Cholybar (Warner-Lambert); Cuemid (Merck & Co.); Quantalan (BMS); Questran (BMS)
Literature References: A synthetic, strongly basic anion exchange resin contg quaternary ammonium functional groups which are attached to a styrene-divinylbenzene copolymer. Main constituent: Polystyrene trimethylbenzylammonium as Cl- anion, also contains divinylbenzene. Av polymeric mol wt >106; Cl- content 14-17%. Effect of particle size on bile salt binding capacity: L. M. Hagerman et al., Proc. Soc. Exp. Biol. Med. 139, 248 (1972). Review of pharmacology: H. R. Casdorph in Lipid Pharmacology Vol. 2(2), R. Paoletti, C. J. Glueck, Eds. (Academic Press, New York, 1976) pp 222-256. Clinical evaluation in chlordecone detoxification: W. J. Cohn et al., N. Engl. J. Med. 298, 243 (1978). Review of pharmacology and therapeutic efficacy: M. Ast, W. H. Frishman, J. Clin. Pharmacol. 30, 99-106 (1990).
Properties: White to buff-colored, hygroscopic, fine powder. Odorless or has not more than a slight amine-like odor. Insol in water, alcohol, benzene, chloroform, ether.
Therap-Cat: Antilipemic; ion-exchange resin (bile salts).
Keywords: Antilipemic; Bile Acid Sequesterants; Ion-exchange Resin.