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CAS No 112192-04-8 , 1H-Indol-5-ol,3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]- Search by region : China

  • Name: 1H-Indol-5-ol,3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-
  • Synonyms: Roxindole;1H-Indol-5-ol,3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-;
  • CAS Registry Number:
  • Flash Point: 302°C
  • Boiling Point: 575.7°Cat760mmHg
  • Density: 1.173g/cm3
  • Refractive index: 1.651
  • Flash Point: 302°C
  • Molecular Weight: 382.93
  • InChI: InChI=1/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2
  • Molecular Formula: C23H26 N2 O
  • Molecular Structure:CAS No:112192-04-8 1H-Indol-5-ol,3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-

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112192-04-8 Roxindole

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112192-04-8 ROXINDOLE HCL

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References of 1H-Indol-5-ol,3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-
Title: Roxindole
CAS Registry Number: 112192-04-8
CAS Name: 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indol-5-ol
Synonyms: 5-hydroxy-3-[4-(1,2,3,6-tetrahydro-4-phenyl-1-pyridyl)butyl]indole
Molecular Formula: C23H26N2O
Molecular Weight: 346.47
Percent Composition: C 79.73%, H 7.56%, N 8.09%, O 4.62%
Literature References: Dopamine D2-receptor agonist. Synthesis: H.-H. Hausberg et al., Acta Pharm. Suec. 1983, Suppl 2, 213; H. B?ttcher et al., J. Med. Chem. 35, 4020 (1992). Pharmacology: C. A. Seyfried et al., Eur. J. Pharmacol. 160, 31 (1989). Clinical pharmacology: K. Wiedemann, M. Kellner, Exp. Clin. Endocrinol. 102, 284 (1994). Clinical evaluation in schizophrenia: H. Wetzel et al., Am. J. Psychiatry 151, 1499 (1994); in depression: G. Gründer et al., Psychopharmacology 111, 123 (1993). Neuroendocrinology in schizophrenics: G. Gründer et al., ibid. 117, 472 (1995).
 
Derivative Type: Hydrochloride
CAS Registry Number: 108050-82-4
Manufacturers' Codes: EMD-38362
Molecular Formula: C23H26N2O.HCl
Molecular Weight: 382.93
Percent Composition: C 72.14%, H 7.11%, N 7.32%, O 4.18%, Cl 9.26%
Properties: Monoclinic crystals, mp 274°.
Melting point: mp 274°
 
Derivative Type: Methanesulfonate
CAS Registry Number: 119742-13-1
Synonyms: Roxindole mesylate
Manufacturers' Codes: EMD-49980
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Dopamine Receptor Agonist.