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CAS No 112809-51-5 , 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile

  • Name: 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
  • Synonyms: 4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile;4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile; Femera; CGS-20267; CGS 20267; 112809-51-5;Femara; Letrozol; Letoval;
  • CAS Registry Number:
  • Melting Point: 181-183 ºC
  • Density: 1.21g/cm3
  • Safety Statements: 36/37/39-26-22
  • Hazard Symbols: Xi: Irritant;C: Corrosive;
  • Molecular Weight: 285.30274
  • InchiKey: HPJKCIUCZWXJDR-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14
    (10-19)4-8-16/h1-8,11-12,17H
  • Risk Statements: 36/37/38-20/21/22
  • Molecular Formula: C17H11N5
  • Molecular Structure:CAS No:112809-51-5 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile

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112809-51-5 Letrozole

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  • Product details: Letrozole (Femara) ( CAS NO.:112809-51-5) Letrozole CAS NO.:112809-51-5 Letrozole Molecular Formula: C17H11N5 Letrozole Molecular Weight: 285.30 Letrozole Assay: 99%min Letrozole Appearance: off-white crystalline powder Letrozole Pac...
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112809-51-5 Letrozole (Femara) CAS NO.:112809-51-5

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  • Quick Detail: 1. CAS No.: 112809-51-5 2. M.F.: C17H11N5 3. M.W.: 285.3 4. Assay: 99% 5. Appearance: White crystalline powder 6. Usage:a powerful Aromatase Inhibitor that was developed to fight breast cancer Hot sell : Dianabol , Testosterone blend , ...
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112809-51-5 Letrozole

  • Letrozole CAS : 112809-51-5 Molecular Formula: C17H11N5 Molecular Weight: 285.31 Molecular Structure: White or light yellow crystal Usage: Used as API in Treatment of breast disease.
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References of 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
Title: Letrozole
CAS Registry Number: 112809-51-5
CAS Name: 4,4￠-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
Synonyms: 1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole; 4-[1-(4-cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile
Manufacturers' Codes: CGS-20267
Trademarks: Femara (Novartis)
Molecular Formula: C17H11N5
Molecular Weight: 285.30
Percent Composition: C 71.57%, H 3.89%, N 24.55%
Literature References: Nonsteroidal aromatase inhibitor; structurally related to fadrozole, q.v. Prepn: R. M. Bowman et al., EP 236940; eidem, US 4978672 (1987, 1990 both to Ciba-Geigy). Pharmacology: A. S. Bhatnagar et al., J. Steroid Biochem. Mol. Biol. 37, 1021 (1990). Clinical suppression of estrogen biosynthesis: L. M. Demers et al., ibid. 44, 687 (1993). EIA and HPLC determn in biological fluids: C. U. Pfister et al., J. Pharm. Sci. 83, 520 (1994). Clinical evaluation in breast cancer: A. Lipton et al., Cancer 75, 2132 (1995). Review of clinical efficacy: P. E. Goss, R. E. Smith, Expert Rev. Anticancer Ther. 2, 249-260 (2002).
Properties: mp 181-183°.
Melting point: mp 181-183°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic (Hormonal); Aromatase Inhibitors; Aromatase Inhibitors.