Home > Name List By 3 > 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3, 4-tetrahydrocarbazol-9-yl]propanoic acid

CAS No 116649-85-5 , 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,
4-tetrahydrocarbazol-9-yl]propanoic acid

  • Name: 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,
    4-tetrahydrocarbazol-9-yl]propanoic acid
  • Synonyms: Baynas (TN); 116649-85-5; Bay u-3405; Bay u 3405; Bay u 3406; Ramatroban (JAN/INN); BAY u3405;Baynas; Bay-u-3405;3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,
    4-tetrahydrocarbazol-9-yl]propanoic acid;
  • CAS Registry Number:
  • Density: 1.43 g/cm3
  • Refractive index: 1.664
  • Molecular Weight: 416.465843
  • InchiKey: LDXDSHIEDAPSSA-OAHLLOKOSA-N
  • InChI: InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,
    28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,
    8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1
  • Molecular Formula: C21H21FN2O4S
  • Molecular Structure:CAS No:116649-85-5 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,<br />4-tetrahydrocarbazol-9-yl]propanoic acid
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116649-85-5 Ramatroban

  • China Beijing Bcory Pharm-chemicals Tech.Co., Ltd. [Manufacturers]
  • Tel: +86-(10)-6087-0891
  • Fax: +86-(10)-6364-8018
  • Address: No 4,Fufeng Road, Gongshanglian Technology Building, Fengtai District, Beijing, Beijing,BeijingChina
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116649-85-5 Ramatroban

  • China Hangzhou Heta Pharm & Chem Co., Ltd. [Manufacturers]
  • Tel: +86-(571)-88298791
  • Fax: +86-(571)-89937386
  • Address: 8# Xiyuan no.1 Road , Westlake Technologe Park, Sandun, Hangzhou 310030, Hangzhou,ZhejiangChina
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116649-85-5 Ramatroban

  • China Yingxuan Chempharm Co.,LTD [Manufacturer]
  • Tel: 86-21-60875125
  • Address: No.2588,Jinhai Rd.pudong,Shanghai,China Shanghai ,nullChina
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116649-85-5 Ramatroban

  • China DRAGONFARM CO., LTD [Manufacturers]
  • Tel: +86-571-85899500/85899501
  • Fax: +86-571-85899502
  • Address: 1001-1002,Huahong Mansion, No.1 Building 238 Tianmushan Road,Hangzhou,China Hangzhou,zhejiangChina
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116649-85-5 Ramatroban

  • China Xiamen Mayah Pharma Co., Ltd. [Manufacturers]
  • Tel: +86-(592)-6806808
  • Fax: +86-(592)-6806809
  • Address: Room 523, Kechuang Building, NO.289, Road Wengjiaolu, Haicang, Xiamen, Fujian 361022, Xiamen,FujianChina
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116649-85-5 Ramatroban

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116649-85-5 Ramatroban

  • China Hangzhou Read Chemical Co., Ltd [Manufacturers]
  • Tel: +86-571-87234293
  • Fax: +86-571-87234255
  • Address: Room 15, 5/F, 40# Qingyunjie, Xiacheng district, Hangzhou, China Hangzhou,zhejiangChina
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References of 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,
4-tetrahydrocarbazol-9-yl]propanoic acid
Title: Ramatroban
CAS Registry Number: 116649-85-5
CAS Name: (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
Synonyms: (+)-(3R)-3-(p-fluorobenzenesulfonamido)-1,2,3,4-tetrahydrocarbazole-9-propionic acid; (+)-3-(4-fluorophenylsulfonamido)-9-(2-carboxyethyl)-1,2,3,4-tetrahydrocarbazole
Manufacturers' Codes: Bay u 3405
Trademarks: Baynas (Bayer)
Molecular Formula: C21H21FN2O4S
Molecular Weight: 416.47
Percent Composition: C 60.56%, H 5.08%, F 4.56%, N 6.73%, O 15.37%, S 7.70%
Literature References: Thromboxane A2 receptor antagonist. Prepn: H. B?shagen et al., DE 3631824; eidem, US 4965258 (1988, 1990 both to Bayer); and absolute configuration: U. Rosentreter et al., Arzneim.-Forsch. 39, 1519 (1989). Series of articles on pharmacology: ibid. 1522-1530. Clinical evaluation in asthma: H. Aizawa et al., Chest 109, 338 (1996).
Properties: Crystals from ether, mp 134-135°. [a]D +70.1° (c = 1.0 in methanol).
Melting point: mp 134-135°
Optical Rotation: [a]D +70.1° (c = 1.0 in methanol)
Therap-Cat: Antiasthmatic; antiallergic.
Keywords: Antiallergic; Antiasthmatic (Nonbronchodilator); Thromboxane A2-Receptor Antagonist.