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CAS No 119169-78-7 , Epristeride Search by region : China

  • Name: Epristeride
  • Synonyms: Epristeride;17-N-tert-Butylcarboxamide androst-3,5-diene-3-carboxylic acid; (17b)-17-[[(1,1-Dimethylethyl)amino]carbonyl]-androsta-3,5-diene-3-carboxylic acid;
  • CAS Registry Number:
  • Flash Point: 314.3°C
  • Boiling Point: 596°Cat760mmHg
  • Density: 1.13g/cm3
  • Refractive index: 1.563
  • Flash Point: 314.3°C
  • Molecular Weight: 399.57
  • InChI: InChI=1/C25H37NO3/c1-23(2,3)26-21(27)20-9-8-18-17-7-6-16-14-15(22(28)29)10-12-24(16,4)19(17)11-13-25(18,20)5/h6,14,17-20H,7-13H2,1-5H3,(H,26,27)(H,28,29)
  • Molecular Formula: C25H37NO3
  • Molecular Structure:CAS No:119169-78-7 Epristeride

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119169-78-7 Epristeride

  • China Inter-Chemical Ltd. [Manufacturers]
  • Tel: +86-(755)-82187211, 82192202
  • Fax: +86-(755)-82187212
  • Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005, Shenzhen,GuangdongChina
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119169-78-7 EPRISTERIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Epristeride
Title: Epristeride
CAS Registry Number: 119169-78-7
CAS Name: (17b)-17-[[(1,1-Dimethylethyl)amino]carbonyl]androsta-3,5-diene-3-carboxylic acid
Synonyms: 17b-(N-tert-butylcarboxamido)androsta-3,5-diene-3-carboxylic acid
Manufacturers' Codes: SKF-105657
Molecular Formula: C25H37NO3
Molecular Weight: 399.57
Percent Composition: C 75.15%, H 9.33%, N 3.51%, O 12.01%
Literature References: 5a-Reductase inhibitor. Prepn and in vitro activity: D. A. Holt et al., EP 289327; eidem, US 4910226 and US 5017568 (1988, 1990, 1991 all to SmithKline Beecham); D. A. Holt et al., J. Med. Chem. 33, 943 (1990). Pharmacology: J. C. Lamb et al., Endocrinology 130, 685 (1992). Antitumor effects in rats: J. C. Lamb et al., Prostate 21, 15 (1992). Mechanism of action study: M. A. Levy et al., Biochemistry 29, 2815 (1990). HPLC determn in human plasma: V. K. Boppana et al., J. Chromatogr. 631, 251 (1993).
Properties: White crystals from ethyl acetate, mp 242-249°. pK 4.8.
Melting point: mp 242-249°
pKa: pK 4.8
Therap-Cat: Treatment of benign prostatic hypertrophy.
Keywords: Antiprostatic Hypertrophy; 5a-Reductase Inhibitor.