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CAS No 123997-26-2 , Eprinomectin Search by region : Germany

  • Name: Eprinomectin
  • Synonyms: 159628-36-1;Eprinomectin; 4''-(acetylamino)-4''-deoxy-;UNII-75KP30FD8O; Avermectin B1; (4''R)-;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 163-166 ºC
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.23
  • Refractive index: 1.567
  • Water Solubility: easily soluble in ethanol, methanol, ethyl acetate and the like, not soluble in water.
  • Safety Statements: 11-20/21/22-36,
  • Hazard Symbols: F,Xn:;
  • Flash Point: °C
  • EINECS: 200-835-2
  • Molecular Weight: 900.10222
  • InchiKey: WPNHOHPRXXCPRA-TVXIRPTOSA-N
  • InChI: InChI=1S/C49H73NO14/c1-25(2)43-28(5)17-18-48(64-43)23-35-20-34(63-48)16-
    15-27(4)44(26(3)13-12-14-33-24-57-46-42(52)29(6)19-36(47(53)60-35)49(33,
    46)54)61-40-22-38(56-11)45(31(8)59-40)62-39-21-37(55-10)41(30(7)58-39)
    50-32(9)51/h12-15,17-19,25-26,28,30-31,34-46,52,54H,16,20-24H2,1-11H3,
    (H,50,51)/b13-12-,27-15-,33-14-/t26-,28-,30-,31-,34+,35-,36-,37+,38-,
    39-,40-,41+,42+,43+,44-,45+,46+,48+,49+/m0/s1
  • Risk Statements: 26-36/37,
  • Molecular Formula: C49H73NO14
  • Molecular Structure:CAS No:123997-26-2 Eprinomectin

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123997-26-2 Eprinomectin

  • Eprinomectin
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of Eprinomectin
Title: Eprinomectin
CAS Registry Number: 123997-26-2
CAS Name: (4¢¢R)-4¢¢-(Acetylamino)-4¢¢-deoxyavermectin B1
Manufacturers' Codes: MK-397
Trademarks: Eprinex (Merck & Co.)
Literature References: Mixture of semisynthetic avermectins, q.v.; containing 90% or more of component B1a and 10% or less of component B1b. Prepn: H. H. Mrozik, US 4427663 (1984 to Merck & Co.). Synthesis: R. J. Cvetovich et al., J. Org. Chem. 59, 7704 (1994) and biological activity: T. K. Jones et al., J. Agric. Food Chem. 42, 1786 (1994). Mechanism of action study: J. P. Arena et al., J. Parasitol. 81, 286 (1995).
Properties: Crystalline solid, mp 163.3-165.7°. LD50 orally in mice: 24 mg/kg (Jones).
Melting point: mp 163.3-165.7°
Toxicity data: LD50 orally in mice: 24 mg/kg (Jones)
 
Derivative Type: Component B1a
CAS Registry Number: 133305-88-1
CAS Name: (4¢¢R)-4¢¢-(Acetylamino)-5-O-demethyl-4¢¢-deoxyavermectin A1a
Molecular Formula: C50H75NO14
Molecular Weight: 914.13
Percent Composition: C 65.69%, H 8.27%, N 1.53%, O 24.50%
 
Derivative Type: Component B1b
CAS Registry Number: 133305-89-2
CAS Name: (4¢¢R)-4¢¢-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4¢¢-deoxy-25-(1-methylethyl)avermectin A1a
Molecular Formula: C49H73NO14
Molecular Weight: 900.10
Percent Composition: C 65.38%, H 8.17%, N 1.56%, O 24.89%
 
Therap-Cat-Vet: Antiparasitic.