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CAS No 1247-42-3 , Meprednisone

  • Name: Meprednisone
  • Synonyms: Meprednisone;17-Hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione;
  • CAS Registry Number:
  • Melting Point: 204-2060C
  • Flash Point: 315.2°C
  • Boiling Point: 574.4°Cat760mmHg
  • Density: 1.28g/cm3
  • Refractive index: 1.595
  • Water Solubility: white solid
  • Flash Point: 315.2°C
  • EINECS: 214-996-1
  • Molecular Weight: 372.46
  • InChI: InChI=1/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h6-7,9,12,15-16,19,23,27H,4-5,8,10-11H2,1-3H3/t12?,15?,16?,19?,20?,21?,22-/m0/s1
  • Molecular Formula: C22H28O5
  • Molecular Structure:CAS No:1247-42-3 Meprednisone

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References of Meprednisone
Title: Meprednisone
CAS Registry Number: 1247-42-3
CAS Name: (16b)-17,21-Dihydroxy-16-methylpregna-1,4-diene-3,11,20-trione
Synonyms: 16b-methylprednisone
Trademarks: Betapred (Schering); Betapar (Parke-Davis); Betalone (Lepetit); Deltisona B
Molecular Formula: C22H28O5
Molecular Weight: 372.45
Percent Composition: C 70.95%, H 7.58%, O 21.48%
Literature References: Prepn: E. P. Oliveto et al., J. Am. Chem. Soc. 80, 4428 (1958); D. Taub et al., ibid. 4435; D. Taub et al., ibid. 82, 4012 (1960); G. G. Nathansohn et al., Experientia 17, 448 (1961); GB 901092 (1962 to Scherico); R. Rausser, E. P. Oliveto, US 3164618 (1965 to Schering).
Properties: Crystals, mp 200-205°. [a]D +200° (dioxane). uv max (methanol): 239 nm (E1%1cm 416).
Melting point: mp 200-205°
Optical Rotation: [a]D +200° (dioxane)
Absorption maximum: uv max (methanol): 239 nm (E1%1cm 416)
 
Derivative Type: 21-Acetate
Molecular Formula: C24H30O6
Molecular Weight: 414.49
Percent Composition: C 69.54%, H 7.30%, O 23.16%
Properties: mp 232-235°. [a]D +210° (dioxane). uv max (methanol): 238 nm (E1%1cm 358).
Melting point: mp 232-235°
Optical Rotation: [a]D +210° (dioxane)
Absorption maximum: uv max (methanol): 238 nm (E1%1cm 358)
 
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.