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CAS No 125-33-7 , 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione Search by region : Canada

  • Name: 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione
  • Synonyms: Mizodin; Sertan; Misodine; Lepsiral;Primaclone;5-ethyl-5-phenyl-1,3-diazinane-4,6-dione; Hexadiona; Mysoline; Mylepsinum; Lepimidin;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 281-282 ºC
  • Flash Point: 228.2°C
  • Boiling Point: 520.7°Cat760mmHg
  • Density: 1.138g/cm3
  • Refractive index: 1.528
  • Water Solubility: <0.1 G/100 ML AT 19 ºC
  • Safety Statements: Poison by ingestion and intraperitoneal routes. Human teratogenic effects include developmental abnormalities of the craniofacial area, skin and skin appendages, and cardiovascular system. Human reproductive effects: effects on newborn, including unusual growth statistics, drug dependence, physical and other neonatal changes. Experimental teratogenic and reproductive effects. Human mutation data reported. An addictive drug. When heated to decomposition it emits toxic fumes of NOx. See also BARBITURATES.
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 228.2°C
  • EINECS: 204-737-0
  • Molecular Weight: 218.25176
  • InchiKey: DQMZLTXERSFNPB-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,
    2,8H2,1H3,(H,13,15)(H,14,16)
  • Risk Statements: 22-40
  • Molecular Formula: C12H14N2O2
  • Molecular Structure:CAS No:125-33-7 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione

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125-33-7 PRIMIDONE-D5

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References of 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione
Title: Primidone
CAS Registry Number: 125-33-7
CAS Name: 5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione
Synonyms: 5-ethyl-5-phenylhexahydropyrimidine-4,6-dione; 2-desoxyphenobarbital
Trademarks: Liskantin (Desitin); Mylepsinum (AWD); Mysoline (Acorus); Resimatil (Sanofi-Synthelabo); Sertan (Valeant)
Molecular Formula: C12H14N2O2
Molecular Weight: 218.25
Percent Composition: C 66.04%, H 6.47%, N 12.84%, O 14.66%
Literature References: Prepd by electrolytic reduction of phenobarbital or by catalytic desulfuration of the corresp 2-thiobarbituric acid: Boon et al., GB 666027 (1952 to I.C.I.); Bogue, Carrington, Br. J. Pharmacol. 8, 230 (1953). Comprehensive description: R. D. Daley in Anal. Profiles Drug Subs. 2, 409-437 (1973); A. A. Al-Badr, H. A. El-Obeid, ibid. 17, 749-795 (1988). HPLC determn in urine: V. Ferranti et al., J. Chromatogr. B 718, 199 (1998). Clinical trial in essential tremor: M. Serrano-Due?as, Parkinsonism Relat. Disord. 10, 29 (2003).
Properties: Crystals, mp 281-282°. Practically tasteless. Has no acidic properties. Sparingly sol in water (0.6 g/l at 37°); in most organic solvents.
Melting point: mp 281-282°
Therap-Cat: Anticonvulsant.
Therap-Cat-Vet: Anticonvulsant. Chiefly to control epileptiform seizures.
Keywords: Anticonvulsant.