Home > Name List By 3 > 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione Germany

CAS No 125-84-8 , 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione Search by region : Germany

  • Name: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
  • Synonyms: Elipten; Orimeten; p-Aminoglutethimide; Aminoglutetimida; dl-Aminoglutethimide;Cytadren;3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione; Aminoglutethimidum; 125-84-8;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 152-154 ºC
  • Density: 1.173 g/cm3
  • Refractive index: 1.566
  • Water Solubility: H2O: 0.2 mg/mL, slightly soluble in water
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 204-756-4
  • Molecular Weight: 232.27834
  • InchiKey: ROBVIMPUHSLWNV-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-
    6H,2,7-8,14H2,1H3,(H,15,16,17)
  • Risk Statements: S26;S36
  • Molecular Formula: C13H16N2O2
  • Molecular Structure:CAS No:125-84-8 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione

Related products

Select to

125-84-8 Aminoglutethimide

  • Aminoglutethimide
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

Select to

1/1
References of 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
Title: Aminoglutethimide
CAS Registry Number: 125-84-8
CAS Name: 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione
Synonyms: 2-(p-aminophenyl)-2-ethylglutarimide; 3-ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine
Trademarks: Cytadren (Novartis); Orimeten (Novartis)
Molecular Formula: C13H16N2O2
Molecular Weight: 232.28
Percent Composition: C 67.22%, H 6.94%, N 12.06%, O 13.78%
Literature References: Aromatase inhibitor; also blocks adrenal steroidogenesis. Formerly used as anticonvulsant. Prepn: K. Hoffmann, E. Urech, US 2848455 (1958 to Ciba). Mass spectrum: G. Ruecker, G. Bohn, Arch. Pharm. 302, 204 (1969). Resolution and abs config of antipodes: N. Finch et al., Experientia 31, 1002 (1975). Comprehensive description: H. Y. Aboul-Enein, Anal. Profiles Drug Subs. 15, 35-69 (1986). Review of pharmacology and clinical use in Cushing's disease and breast cancer: R. J. Santen, R. I. Misbin, Pharmacotherapy 1, 95-120 (1981); in prostate cancer: K. A. Havlin, D. L. Trump, Cancer Treat. Res. 39, 83-96 (1988).
Properties: Crystals from methanol or ethyl acetate, mp 149-150°. Freely sol in most organic solvents; poorly sol in ethyl acetate, 0.1N HCl and absolute ethanol; readily sol in acetone and 100% acetic acid. Practically insol in water.
Melting point: mp 149-150°
Therap-Cat: Adrenocortical suppressant; antineoplastic.
Keywords: Anticonvulsant; Antineoplastic (Hormonal); Antiadrenals; Aromatase Inhibitors; Aromatase Inhibitors; Adrenocortical Suppressant.