Home > Name List By other > (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2, 4'-cyclohex-2-ene]-1',3-dione China

CAS No 126-07-8 , (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,
4'-cyclohex-2-ene]-1',3-dione Search by region : China

  • Name: (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,
    4'-cyclohex-2-ene]-1',3-dione
  • Synonyms: Grizeofulvin; Grisofulvin;(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,
    4'-cyclohex-2-ene]-1',3-dione; Grifulvin V; Spirofulvin; Fulvicin; (+)-Griseofulvin;Grisactin; Grisefuline; Grisovin;
  • CAS Registry Number:
  • Melting Point: 217-224 ºC
  • Flash Point: 228°C
  • Boiling Point: 570.4°Cat760mmHg
  • Density: 1.38g/cm3
  • Refractive index: 1.565
  • Alpha: 354 º (C=1, DIMETHYLFORM)
  • Safety Statements: R60;R61;R40;R43
  • Hazard Symbols: T: Toxic;
  • Flash Point: 228°C
  • EINECS: 204-767-4
  • Molecular Weight: 352.76628
  • InchiKey: DDUHZTYCFQRHIY-RBHXEPJQSA-N
  • InChI: InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-
    3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
  • Risk Statements: S53;S22;S36/37/39;S45
  • Molecular Formula: C17H17ClO6
  • Molecular Structure:CAS No:126-07-8 (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,<br />4'-cyclohex-2-ene]-1',3-dione

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126-07-8 Griseofulvin

  • Basic Info Product name:Griseofulvin Other name:grisovin;(+)-Griseofulvin CAS No.:126-07-8 Assay:97.0%~102.0% M.F.:C17H19ClO6 M.W.:354.7822 Reference standard:BP2005/EP5/CP2010 Appearance:White or white crystalline powder Company profile: We are Wuha...
  • China Wuhan Magic Biotechnology CO.Ltd [Manufacturer, Trading Company]
  • Tel: 86-027-55234455
  • Address: Xiongchu Avenue No.209 Wuhan,HubeiChina
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126-07-8 Griseofulvin grisovin

  • Basic Info Product name:Griseofulvin Other name:grisovin;(+)-Griseofulvin CAS No.:126-07-8 Assay:97.0%~102.0% M.F.:C17H19ClO6 M.W.:354.7822 Reference standard:BP2005/EP5/CP2010 Appearance:White or white crystalline powder Company profile: We are Wuha...
  • China Wuhan Magic Biotechnology CO.Ltd [Manufacturer, Trading Company]
  • Tel: 86-027-55234455
  • Address: Xiongchu Avenue No.209 Wuhan,HubeiChina
Contact Supplier

126-07-8 Griseofulvin

  • Basic Info Product name:Griseofulvin Other name:grisovin;(+)-Griseofulvin CAS No.:126-07-8 Assay:97.0%~102.0% M.F.:C17H19ClO6 M.W.:354.7822 Reference standard:BP2005/EP5/CP2010 Appearance:White or white crystalline powder Our Advantages: 1.Rich exper...
  • China Bettli Industry Limited [Manufacturer, Trading Company]
  • Tel: 86-852-99657666
  • Address: Kaiser Certre No. 18 Centre Street Hong Kong,HubeiChina
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126-07-8 Griseofulvin

  • Griseofulvin Product name: Griseofulvin Other name: grisovin;(+)-Griseofulvin CAS No.: 126-07-8 Assay: 97.0%~102.0% Packing: 20kg/drum M.F.: C17H19ClO6 M.W.: 354.7822 Reference standard: BP2005/EP5/CP2010 Appearance: White or white crystalline powder
  • China Hubei Yuancheng Pharmaceutical Co., Ltd [Manufacturer]
  • Tel: 086-027-50756084
  • Fax: --
  • Address: Zhongshan Road Wuhan,HubeiChina
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126-07-8 (+)-Griseofulvin

  • Catalog No. LS50179 Cas No. 126-07-8 Product Name: (+)-Griseofulvin Molecular Formula: C17H17ClO6 Formula Weight: 352.77
  • China Aromalake Chemical Co., Ltd. [Manufacturer]
  • Tel: 86-571-57104378
  • Fax: --
  • Address: Hangzhou West Lake Science and Technology Park Hangzhou,ZhejiangChina
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126-07-8 (+)-Griseofulvin Skype bran at ycphar dot com

  • Basic Info Name:(+)-Griseofulvin Apearance:White Powder CAS:126-07-8 MF:C17H17ClO6 MW:352.77 Shipment:Air/Sea/EMS,DHL,TNT,UPS,Fedx Package:20kg/Cardboard Barrel Payment: Bank Transfer,Bitcoin,WU,MoneyGram Trademark:YuanChen Origin:China Price:fluctua...
  • Min. Order: 1000
  • China Yuan Chen Co. Ltd [Manufacturer]
  • Tel: 86-027-50756092
  • Address: 496 Zhongshan Road Wuhan,HubeiChina
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126-07-8 CAS:126-07-8 (+)-Griseofulvin

  • Basic Info Name:(+)-Griseofulvin Apearance:White Powder CAS:126-07-8 MF:C17H17ClO6 MW:352.77 Shipment:Air/Sea/EMS,DHL,TNT,UPS,Fedx Package:20kg/Cardboard Barrel Payment: Bank Transfer,Bitcoin,WU,MoneyGram Trademark:YuanChen Origin:China Price:fluctua...
  • Min. Order: 1000
  • China YuanChne Co. Ltd [Manufacturer]
  • Tel: 86-027-50756092
  • Address: 496 Zhongshan Road Wuhan,HubeiChina
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126-07-8 MF: C17H17ClO6 (+)-Griseofulvin

  • Basic Info Name:(+)-Griseofulvin Apearance:White Powder CAS:126-07-8 MF:C17H17ClO6 MW:352.77 Shipment:Air/Sea/EMS,DHL,TNT,UPS,Fedx Package:20kg/Cardboard Barrel Payment: Bank Transfer,Bitcoin,WU,MoneyGram Trademark:YuanChen Origin:China Price:fluctua...
  • Min. Order: 1000
  • China YuanChen Co. Ltd [Manufacturer]
  • Tel: 86-5075-6092
  • Address: 496 ZhongShan Road Wuhan,nullChina
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126-07-8 China Factory Price (+)-Griseofulvin

  • Basic Info Name:(+)-Griseofulvin Apearance:White Powder CAS:126-07-8 MF:C17H17ClO6 MW:352.77 Shipment:Air/Sea/EMS,DHL,TNT,UPS,Fedx Package:20kg/Cardboard Barrel Payment: Bank Transfer,Bitcoin,WU,MoneyGram Trademark:YuanChen Origin:China Price:fluctua...
  • Min. Order: 1000
  • China YuanChen Co. Ltd [Manufacturer]
  • Tel: 86-5075-6206
  • Fax: --
  • Address: 496 ZhongShan Road. Wuhan,HubeiChina
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126-07-8 (+)-Griseofulvin

  • (+)-Griseofulvin Synonyms:(+)-GRISEOFULVIN;GRISEOFULVIN;[2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE;(2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-...
  • Min. Order: 10000
  • FOB Price: USD1 - 2 /
  • China Zhuhaishi Shuangbojie Technology Co.,Ltd. [Manufacturer]
  • Tel: 86-0756-8889897
  • Fax: 86-0756-8889806
  • Address: NO.101,Guofang Road,Gongbei,Zhuhai zhuhai,GuangdongChina
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References of (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,
4'-cyclohex-2-ene]-1',3-dione
Title: Griseofulvin
CAS Registry Number: 126-07-8
CAS Name: (1¢S,6¢R)-7-Chloro-2¢,4,6-trimethoxy-6¢-methylspiro[benzofuran-2(3H),1¢-[2]cyclohexene]-3,4¢-dione
Synonyms: 7-chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1¢-(2¢-methoxy-6¢-methylcyclohex-2¢-en-4¢-one); amudane; Curling factor
Trademarks: Fulcin (Zeneca); Fulvicin (Schering); Grifulvin (McNeil); Grisactin (Ayerst); Griséfuline (Sanofi Winthrop); Grisovin (GSK); Gris-PEG (Herbert); Grysio (Ayerst); Lamoryl (Leo Pharm); Likuden (HMR); Polygris (Essex); Poncyl-FP (Takeda); Spirofulvin; Sporostatin (Schering)
Molecular Formula: C17H17ClO6
Molecular Weight: 352.77
Percent Composition: C 57.88%, H 4.86%, Cl 10.05%, O 27.21%
Literature References: Antibiotic substance produced by Penicillium griseofulvum Dierckx and by P. janczewskii Zal. [same as P. nigricans (Banier)Thom]. Isoln: Oxford et al., Biochem. J. 33, 240 (1939); Brian et al., Trans. Br. Mycol. Soc. 29, 173 (1946); Hockenhull, Dorey et al., US 3069328, US 3069329 (both 1962 to Glaxo). Structure: Grove et al., Chem. Ind. (London) 1951, 219; J. Chem. Soc. 1952, 3977. Stereochemistry: MacMillan, ibid. 1959, 1823; Brown, Sim, ibid. 1963, 1050. Total synthesis: Brossi et al., Helv. Chim. Acta 43, 1444, 2071 (1960); Taub et al., Tetrahedron 19, 1 (1963); Stork, Tomasz, J. Am. Chem. Soc. 86, 471 (1964); S. Danishefsky, F. J. Walker, ibid. 101, 7018 (1979). Conformation: Levine, Hicks, Tetrahedron Lett. 1971, 311. Crystal structure: G. Malmros et al., Cryst. Struct. Commun. 6, 463 (1977). Review and evaluation of studies of carcinogenic action in laboratory animals: IARC Monographs 10, 153-161 (1976). Review: Grove, Q. Rev. Chem. Soc. 17, 1 (1963); Huber in Antibiotics vol. 3, J. W. Corcoran, F. E. Hahn, Eds. (Springer-Verlag, New York, 1975) pp 606-613. Comprehensive description: E. R. Townley, Anal. Profiles Drug Subs. 8, 219-249 (1979).
Properties: Stout octahedra or rhombs from benzene, mp 220°. [a]D17 +370° (satd CHCl3 soln). uv max: 286, 325 nm. Soly in DMF at 25°: 12 to 14 g/100 ml. Slightly sol in ethanol, methanol, acetone, benzene, CHCl3, ethyl acetate, acetic acid. Practically insol in water, petr ether.
Melting point: mp 220°
Optical Rotation: [a]D17 +370° (satd CHCl3 soln)
Absorption maximum: uv max: 286, 325 nm
Therap-Cat: Antifungal.
Therap-Cat-Vet: Antifungal.
Keywords: Antifungal (Antibiotics).