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CAS No 126544-47-6 , Ciclesonide

  • Name: Ciclesonide
  • Synonyms: (R)-11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde 21-isobutyrate;Ciclesonide;
  • CAS Registry Number:
  • Density: 1.23 g/cm3
  • Molecular Weight: 540.69
  • InChI: InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1
  • Molecular Formula: C32H44O7
  • Molecular Structure:CAS No:126544-47-6 Ciclesonide

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126544-47-6 Ciclesonide

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126544-47-6 Pregna-1,4-diene-3,20-dione,16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)-,(11b,16a)-

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126544-47-6 Ciclesonide

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126544-47-6; 141845-82-1 Ciclesonide

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126544-47-6 CICLESONIDE

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126544-47-6 Pregna-1,4-diene-3,20-dione,16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)-,(11b,16a)-

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References of Ciclesonide
Title: Ciclesonide
CAS Registry Number: 126544-47-6
CAS Name: (11b,16a)-16,17-[[(R)-Cyclohexylmethylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)pregna-1,4-diene-3,20-dione
Manufacturers' Codes: BY-9010
Trademarks: Alvesco (Altana)
Molecular Formula: C32H44O7
Molecular Weight: 540.69
Percent Composition: C 71.08%, H 8.20%, O 20.71%
Literature References: Inhaled corticosteroid. Prodrug converted to the active metabolite, ciclesonide-active principle, in the lung. Prepn: J. Calatayud et al., DE 4129535; eidem, US 5482934 (1992, 1996 both to Elmu). Pharmacokinetics and pharmacodynamics: S. Rohatagi et al., J. Clin. Pharmacol. 43, 365 (2003). Clinical evaluation in asthma: D. A. Taylor et al., Am. J. Respir. Crit. Care Med. 160, 237 (1999); in allergic rhinitis: B. M. W. Schmidt et al., J. Clin. Pharmacol. 39, 1062 (1999). Review of clinical experience: G. Dent, Curr. Opin. Invest. Drugs 3, 78-83 (2002).
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.