Home > Name List By 1 > 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4- oxoquinoline-3-carboxylic acid

CAS No 127294-70-6 , 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-
oxoquinoline-3-carboxylic acid

  • Name: 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-
    oxoquinoline-3-carboxylic acid
  • Synonyms: 127294-70-6; NCGC00167532-01; DSSTox_RID_81829; Q 35;1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-
    oxoquinoline-3-carboxylic acid; AG-D-56934; Balofloxacin [INN]; Baloxin; DSSTox_CID_26695;
  • CAS Registry Number:
  • Melting Point: 137 ºC
  • Density: 1.4 g/cm3
  • Refractive index: 1.639
  • Molecular Weight: 389.420663
  • InchiKey: MGQLHRYJBWGORO-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H24FN3O4/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)
    24(12-5-6-12)10-14(18(13)25)20(26)27/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,
    27)
  • Molecular Formula: C20H24FN3O4
  • Molecular Structure:CAS No:127294-70-6 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-<br />oxoquinoline-3-carboxylic acid

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References of 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-
oxoquinoline-3-carboxylic acid
Title: Balofloxacin
CAS Registry Number: 127294-70-6
CAS Name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidinyl]-4-oxo-3-quinolinecarboxylic acid
Manufacturers' Codes: Q-35
Trademarks: Baloxin (Chugai)
Molecular Formula: C20H24FN3O4
Molecular Weight: 389.42
Percent Composition: C 61.69%, H 6.21%, F 4.88%, N 10.79%, O 16.43%
Literature References: Fluorinated quinolone antibacterial. Prepn: H. Nagano et al., EP 342675; eidem, US 5051509 (1989, 1991 both to Chugai). Photostability: K. Marutani et al., Antimicrob. Agents Chemother. 37, 2217 (1993). Comparative antibacterial spectrum: H. Iwasaki et al., Chemotherapy (Basel) 41, 100 (1995). Pharmacokinetics: T. Nakagawa et al., Arzneim.-Forsch. 45, 719 (1995). HPLC determn in biological fluids: T. Nakagawa et al., ibid. 716. Clinical evaluation in respiratory tract infection: O. Kunii, F. Matsumoto, Proc. 18th Int. Congr. Chemother., Stockholm 1993, 22-23; in urinary tract infection: J. Kumazawa, F. Matsumoto, ibid., 69-70.
Properties: Colorless needles from acetonitrile-water, mp 134-135°.
Melting point: mp 134-135°
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.