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CAS No 129-20-4 , 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione Search by region : China

  • Name: 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione
  • Synonyms: Oxiphenbutazone; Butapirone; Etrozolidina; Tandearil;4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione; Oxyphenylbutazone; Tanderil; Butaflogin; Oxazolidin; Idrobutazina;
  • CAS Registry Number:
  • Flash Point: 247.5°C
  • Boiling Point: 485.6°Cat760mmHg
  • Density: 1.241g/cm3
  • Refractive index: 1.61
  • Safety Statements: A poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic to humans by ingestion. Human systemic effects: agranulocytosis, dermatitis, diarrhea, fever, hemorrhage, hepatitis, hypermotility, nausea or vomiting, salivary gland changes, thrombocytopenia. Experimental reproductive effects. Questionable carcinogen. Mutation data reported. Used as an anti-inflammatory agent. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 247.5°C
  • EINECS: 204-936-2
  • Molecular Weight: 324.3737
  • InchiKey: HFHZKZSRXITVMK-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H20N2O3/c1-2-3-9-17-18(23)20(14-7-5-4-6-8-14)21(19(17)24)15-
    10-12-16(22)13-11-15/h4-8,10-13,17,22H,2-3,9H2,1H3
  • Molecular Formula: C19H20N2O3
  • Molecular Structure:CAS No:129-20-4 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione

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References of 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione
Title: Oxyphenbutazone
CAS Registry Number: 129-20-4
CAS Name: 4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione
Synonyms: 4-butyl-2-(p-hydroxyphenyl)-1-phenyl-3,5-pyrazolidinedione; 1-phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-n-butylpyrazolidine; 1-(p-hydroxyphenyl)-2-phenyl-4-butylpyrazolidine-3,5-dione; p-hydroxyphenylbutazone
Manufacturers' Codes: G-27202
Trademarks: Californit (Merckle); Crovaril; Flogitolo; Flogoril; Frabel; Neo-Farmadol; Oxalid (USV); Rapostan (Mepha); Tandearil (Novartis); Visubutina
Molecular Formula: C19H20N2O3
Molecular Weight: 324.37
Percent Composition: C 70.35%, H 6.21%, N 8.64%, O 14.80%
Literature References: Prepn: Hafliger, US 2745783 (1956 to Geigy); Pfister, Hafliger, Helv. Chim. Acta 40, 395 (1957).
 
Derivative Type: Monohydrate
CAS Registry Number: 7081-38-1
Trademarks: Imbun (Merckle); Phlogistol (Spitzner); Phlogase (Adenylchemie); Phlogont (Azupharma)
Properties: Crystals, mp 96°. Anhydr crystals from ether + petr ether, mp 124-125°. Acidic reaction. Soluble in ethanol, methanol, chloroform, benzene, ether. Forms a water-soluble sodium salt.
Melting point: mp 96°; mp 124-125°
 
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Pyrazolones.