Home > Name List By 3 > 3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Switzerland

CAS No 132203-70-4 , 3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl]
2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Search by region : Switzerland

  • Name: 3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl]
    2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Synonyms: Atelec (TN); 132203-70-4; Cilnidipine [INN]; FRC-8653; FRC 8653;Cinalong; Atelec; Siscard;3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl]
    2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; Cinaldipine;
  • CAS Registry Number:
  • Melting Point: 97-99ºC
  • Flash Point: 348.5ºC
  • Boiling Point: 652.6ºCat760mmHg
  • Density: 1.24g/cm3
  • Refractive index: 1.581
  • Flash Point: 348.5ºC
  • Molecular Weight: 492.52042
  • InchiKey: KJEBULYHNRNJTE-DHZHZOJOSA-N
  • InChI: InChI=1S/C27H28N2O7/c1-18-23(26(30)35-14-8-11-20-9-5-4-6-10-20)25(21-12-
    7-13-22(17-21)29(32)33)24(19(2)28-18)27(31)36-16-15-34-3/h4-13,17,25,
    28H,14-16H2,1-3H3/b11-8+
  • Molecular Formula: C27H28N2O7
  • Molecular Structure:CAS No:132203-70-4 3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl]<br />2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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132203-70-4 Cilnidipine

  • Cilnidipine, > 98%
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
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132203-70-4 Cilnidipine

  • Switzerland Biotrend Chemicals AG [Importer/Exporter]
  • Tel: +41-(44)-805 76 76
  • Fax: +41-(44)-805 76 77
  • Address: Unterdorfstr. 21b, Wangen/Zuerich CH-8602, Wangen/Zürich,nullSwitzerland
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References of 3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl]
2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Title: Cilnidipine
CAS Registry Number: 132203-70-4
CAS Name: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl (2E)-3-phenyl-2-propenyl ester
Synonyms: (±)-(E)-cinnamyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
Manufacturers' Codes: FRC-8653
Trademarks: Atelec (Morishita); Cinalong (Fujirebio); Siscard (Boehringer, Ing.)
Molecular Formula: C27H28N2O7
Molecular Weight: 492.52
Percent Composition: C 65.84%, H 5.73%, N 5.69%, O 22.74%
Literature References: Dihydropyridine calcium channel blocker. Prepn: T. Kutsuma et al., EP 161877; eidem, US 4672068 (1985, 1987 both to Fujirebio). Pharmacology: K. Ikeda et al., Oyo Yakuri 44, 433 (1992). Mechanism of action study: M. Hosono et al., J. Pharmacobio-Dyn. 15, 547 (1992). LC-MS determn in plasma: K. Hatada et al., J. Chromatogr. 583, 116 (1992). Clinical study: M. Ishii, Jpn. Pharmacol. Ther. 21, 59 (1993). Acute toxicity study: S. Wada et al., Yakuri to Chiryo 20, Suppl. 7, S1683 (1992), C.A. 118, 32711 (1992).
Properties: Crystals from methanol, mp 115.5-116.6°. LD50 in male, female mice, rats (mg/kg): 35000, 35000, 35000, 4412 orally; 35000 all species s.c.; 1845, 2353, 441, 426 i.p. (Wada).
Melting point: mp 115.5-116.6°
Toxicity data: LD50 in male, female mice, rats (mg/kg): 35000, 35000, 35000, 4412 orally; 35000 all species s.c.; 1845, 2353, 441, 426 i.p. (Wada)
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Dihydropyridine Derivatives; Calcium Channel Blocker; Dihydropyridine Derivatives.