Home > Name List By other > [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino] propoxy]phenyl]... Germany

CAS No 133242-30-5 , [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl
3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]
propoxy]phenyl]propanoate Search by region : Germany

  • Name: [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl
    3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]
    propoxy]phenyl]propanoate
  • Synonyms: 133242-30-5;Ono 1101;[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl
    3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]
    propoxy]phenyl]propanoate;
  • CAS Registry Number:
  • Density: 1.201 g/cm3
  • Molecular Weight: 509.59246
  • InchiKey: WMDSZGFJQKSLLH-RBBKRZOGSA-N
  • InChI: InChI=1S/C25H39N3O8/c1-25(2)35-18-22(36-25)17-34-23(30)8-5-19-3-6-21(7-
    4-19)33-16-20(29)15-26-9-10-27-24(31)28-11-13-32-14-12-28/h3-4,6-7,20,
    22,26,29H,5,8-18H2,1-2H3,(H,27,31)/t20-,22+/m0/s1
  • Molecular Formula: C25H39N3O8
  • Molecular Structure:CAS No:133242-30-5 [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl<br />3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]<br />propoxy]phenyl]propanoate

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133242-30-5 Landiolol

  • Landiolol
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl
3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]
propoxy]phenyl]propanoate
Title: Landiolol
CAS Registry Number: 133242-30-5
CAS Name: 4-[(2S)-2-Hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]benzenepropanoic acid [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester
Synonyms: (-)-2,2-dimethyl-1,3-dioxolan-4S-ylmethyl 3-[4-[3-[2-(morpholinocarbonylamino)ethylamino]-2S-hydroxypropoxy]phenyl]propionate
Molecular Formula: C25H39N3O8
Molecular Weight: 509.59
Percent Composition: C 58.92%, H 7.71%, N 8.25%, O 25.12%
Literature References: Cardioselective b-adrenergic blocker. Prepn: S. Iguchi et al., EP 397031; US 5013734 (1990, 1991 both to Ono Pharm.); idem et al., Chem. Pharm. Bull. 40, 462 (1992). Electrophysiology: A. Sugiyama et al., J. Cardiovasc. Pharmacol. 34, 70 (1999). Clinical pharmacology: A. Kitamura et al., Eur. J. Clin. Pharmacol. 51, 467 (1997). Clinical pharmacokinetics in patients with cardiac tachyarrhythmias: H. Atarashi et al., Clin. Pharmacol. Ther. 68, 143 (2000).
 
Derivative Type: Hydrochloride
CAS Registry Number: 144481-98-1
Manufacturers' Codes: ONO-1101
Trademarks: Onoact (Ono)
Molecular Formula: C25H39N3O8.HCl
Molecular Weight: 546.05
Percent Composition: C 54.99%, H 7.38%, N 7.70%, O 23.44%, Cl 6.49%
Properties: mp 125.4°. LD50 in mice (mg/kg): 290 i.v. (Iguchi).
Melting point: mp 125.4°
Toxicity data: LD50 in mice (mg/kg): 290 i.v. (Iguchi)
 
Therap-Cat: Antiarrhythmic.
Keywords: Antiarrhythmic; ?Adrenergic Blocker.