Home > Name List By 1 > 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ China

CAS No 135-09-1 , 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ Search by region : China

  • Name: 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ
  • Synonyms: Diurometon;1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ Enjit; Hidroflumetiazid; Robezon;Diuredemina;6,2,
    4-benzothiadiazine-7-sulfonamide; Hidroalogen; Glomerulin; Spandiuril; Flutizide;
  • CAS Registry Number:
  • Melting Point: 272-273
  • Flash Point: 275.3°C
  • Boiling Point: 531.6°C at 760 mmHg
  • Density: 1.678g/cm3
  • Refractive index: 1.55
  • Safety Statements: S36
  • Hazard Symbols: Xn,Xi
  • Flash Point: 275.3°C
  • EINECS: 205-173-8
  • Molecular Weight: 331.29203
  • InchiKey: DMDGGSIALPNSEE-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H8F3N3O4S2/c9-8(10,11)4-1-5-7(2-6(4)19(12,15)16)20(17,
    18)14-3-13-5/h1-2,13-14H,3H2,(H2,12,15,16)
  • Risk Statements: 42/43
  • Molecular Formula: C8H8F3N3O4S2
  • Molecular Structure:CAS No:135-09-1 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ

Related products

Select to

135-09-1 Hydroflumethiazide

  • Hydroflumethiazide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

135-09-1 Hudroflumethiazide

  • Hudroflumethiazide, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

135-09-1 Hydroflumethiazide

Contact Supplier

135-09-1 2H-1,2,4-Benzothiadiazine-7-sulfonamide,3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide

  • China Meryer Chemical Technology Co., Ltd [Manufacturers]
  • Tel: +86-(0)755-86170218
  • Fax: +86-(0)755-86170066
  • Address: Room 23A, Building 4, Fashion House,Chuangye Road, Nanshan District shenzhen,shenzhenChina
Contact Supplier

135-09-1 2H-1,2,4-Benzothiadiazine-7-sulfonamide,3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide

  • China Shanghai CelChem Company [Manufacturers]
  • Tel: +86-(21)-64573501, 64573502
  • Fax: +86-(21)-64573822
  • Address: Room 210, Zhonghuang Building, No. 1007, 2nd South Zongshan Road, Shanghai 200030, shanghai,ShanghaiChina
Contact Supplier

135-09-1 3,4-DIHYDRO-6-(TRIFLUOROMETHYL)-2H-1,2,4-BENZOTHIADIAZINE-7-SULPHONAMIDE-1,1-DIOXIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ
Title: Hydroflumethiazide
CAS Registry Number: 135-09-1
CAS Name: 3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Synonyms: 6-trifluoromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide; 3,4-dihydro-7-sulfamyl-6-trifluoromethyl-1,2,4-benzothiadiazine 1,1-dioxide; trifluoromethylhydrothiazide; dihydroflumethiazide; methforylthiazidine; metflorylthiazidine
Trademarks: Diucardin (Ayerst); Elodrine; Finuret; Hydol; Hydrenox (Boots); Leodrine (Leo Pharm); NaClex (Glaxo); Rodiuran; Rontyl (Leo Pharm); Saluron (Apothecon); Sisuril; Vergonil
Molecular Formula: C8H8F3N3O4S2
Molecular Weight: 331.29
Percent Composition: C 29.00%, H 2.43%, F 17.20%, N 12.68%, O 19.32%, S 19.36%
Literature References: Synthesis: Holdrege et al., J. Am. Chem. Soc. 81, 4807 (1959); Close et al., ibid. 82, 1132 (1960); Yale et al., ibid. 2042; Novello et al., J. Org. Chem. 25, 970 (1960). Numerous patents, e.g., Lund et al., US 3254076 (1966 to L?vens Kemiske Fabrik). Pharmacology: J. J. Piala et al., J. Pharmacol. Exp. Ther. 134, 273 (1961). Comprehensive description: C. E. Orzech et al., Anal. Profiles Drug Subs. 7, 297-317 (1978).
Properties: Crystals, mp 272-273°. uv max (methanol): 272.5 nm (log e 4.286). Soly in mg/ml at 25°: acetone >100; methanol 58; acetonitrile 43; water 0.3; ether 0.2; benzene <0.1. pK1 8.9; pK2 10.7. Forms water-sol salts with bases. LD50 in mice (mg/kg): >8000 orally, 750 i.v., 6280 i.p. (Piala).
Melting point: mp 272-273°
pKa: pK1 8.9; pK2 10.7
Absorption maximum: uv max (methanol): 272.5 nm (log e 4.286)
Toxicity data: LD50 in mice (mg/kg): >8000 orally, 750 i.v., 6280 i.p. (Piala)
Therap-Cat: Antihypertensive; diuretic.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs.