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CAS No 13710-19-5 , 2-(3-chloro-2-methylanilino)benzoic acid Search by region : India

  • Name: 2-(3-chloro-2-methylanilino)benzoic acid
  • Synonyms: Acidum tolfenamicum; N-(3-Chloro-2-methylphenyl)anthranilic acid;2-(3-chloro-2-methylanilino)benzoic acid; Acide tolfenamique;13710-19-5; Acido tolfenamico;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 210-214 ºC
  • Boiling Point:
  • Density: 1.333 g/cm3
  • Refractive index: 1.658
  • Water Solubility: Insoluble
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 237-264-3
  • Molecular Weight: 261.70358
  • InchiKey: YEZNLOUZAIOMLT-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/
    h2-8,16H,1H3,(H,17,18)
  • Risk Statements: R22
  • Molecular Formula: C14H12ClNO2
  • Molecular Structure:CAS No:13710-19-5 2-(3-chloro-2-methylanilino)benzoic acid

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References of 2-(3-chloro-2-methylanilino)benzoic acid
Title: Tolfenamic Acid
CAS Registry Number: 13710-19-5
CAS Name: 2-[(3-Chloro-2-methylphenyl)amino]benzoic acid
Synonyms: N-(3-chloro-o-tolyl)anthranilic acid; N-(2-methyl-3-chlorophenyl)anthranilic acid
Manufacturers' Codes: GEA-6414
Trademarks: Clotam (GEA); Tolfedine (V oquinol); Tolfine (V oquinol)
Molecular Formula: C14H12ClNO2
Molecular Weight: 261.70
Percent Composition: C 64.25%, H 4.62%, Cl 13.55%, N 5.35%, O 12.23%
Literature References: Deriv of anthranilic acid, related structurally to mefenamic and flufenamic acids, q.q.v. Prepn: NL 6600251 (1966 to Gea A/S), C.A. 66, 2377 (1967); R. A. Scherrer, F. W. Short, US 3313848 (1967 to Parke, Davis). Inhibition of prostaglandin biosynthesis: I. B. Linden et al., Scand. J. Rheumatol. 5, 129 (1976). HPLC determn: F. Nielsen-Kudsk, Acta Pharmacol. Toxicol. 47, 267 (1980). Metabolism: T. Kuninaka et al., Yakugaku Zasshi 101, 232 (1981), C.A. 95, 168 (1981). Human pharmacokinetics: P. Pentikaeinen et al., Eur. J. Clin. Pharmacol. 19, 359 (1981). Pharmacological studies: S. Yamashita et al., Toho Igakkai Zasshi 28, 76-105 (1981), C.A. 95, 16183, 180846 (1981). Clinical study: V. Rejholec et al., Scand. J. Rheumatol. Suppl. 33, 50 (1980); Suppl. 36, 1 (1980).
Properties: Crystals from abs ethanol, mp 207-207.5°.
Melting point: mp 207-207.5°
Therap-Cat: Anti-inflammatory; analgesic.
Therap-Cat-Vet: Anti-inflammatory.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Aminoarylcarboxylic Acid Derivatives.