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CAS No 13838-16-9 , 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane Search by region : China

  • Name: 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
  • Synonyms: Ethrane;2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane; Alyrane; Methylflurether; Anesthetic 347; Anesthetic Compound No. 347; 13838-16-9; Efrane; Compound 347;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: 59.9°Cat760mmHg
  • Density: 1.489g/cm3
  • Refractive index: 1.303
  • Safety Statements: Mildly toxic by inhalation, ingestion, and subcutaneous routes. Human systemic effects by inhalation: decreased urine volume or anuria. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. An eye irritant. Questionable carcinogen with experimental carcinogenic data. An anesthetic. When heated to decomposition it emits very toxic fumes of F− and Cl−. See also
  • Hazard Symbols: Volatile with anesthetic properties, but nonflammable. TLV: 75 ppm; not classifiable as a human carcinogen.
  • Flash Point: °C
  • EINECS: 237-553-4
  • Molecular Weight: 184.492396
  • InchiKey: JPGQOUSTVILISH-UHFFFAOYSA-N
  • InChI: InChI=1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H
  • Risk Statements: 36
  • Molecular Formula: C3H2ClF5O
  • Molecular Structure:CAS No:13838-16-9 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane

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References of 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
Title: Enflurane
CAS Registry Number: 13838-16-9
CAS Name: 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
Synonyms: 2-chloro-1,1,2-trifluoroethyl difluoromethyl ether; methylflurether
Manufacturers' Codes: compd 347; NSC-115944
Trademarks: Alyrane (Baxter); Efrane (Abbott); Ethrane (Baxter)
Molecular Formula: C3H2ClF5O
Molecular Weight: 184.49
Percent Composition: C 19.53%, H 1.09%, Cl 19.22%, F 51.49%, O 8.67%
Line Formula: CHF2OCF2CHClF
Literature References: Prepn by fluorination of the corresp dichloromethyl ether: R. C. Terrell, GB 1138406; idem, US 3469011; US 3527813 (1969, 1969, 1970 all to Air Reduction). Synthesis and anesthetic properties: R. C. Terrell et al., J. Med. Chem. 14, 517 (1971); 15, 604 (1972). Enantiomeric resolution: J. Meinwald et al., Science 251, 560 (1991).
Properties: Stable, volatile, non-flammable liq. bp 56.5°. nD20 1.3025. d2525 1.5167. Does not degrade in the presence of alkali or light. Miscible with other organic liquids incl. fats and oils.
Boiling point: bp 56.5°
Index of refraction: nD20 1.3025
Density: d2525 1.5167
CAUTION: Potential symptoms of overexposure are eye irritation; CNS depression, analgesia, anesthesia, seizures, respiratory depression. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 128.
Therap-Cat: Anesthetic (inhalation).
Keywords: Anesthetic (Inhalation).