Home > Name List By other > (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3, 2-e]thiazine-6-sulfonamide

CAS No 138890-62-7 , (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,
2-e]thiazine-6-sulfonamide

  • Name: (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,
    2-e]thiazine-6-sulfonamide
  • Synonyms: 138890-62-7; Azopt (TN); AC1L2AKA; Brinzolamide (BRZ); 3znc;(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,
    2-e]thiazine-6-sulfonamide; Brinzolamide [USAN]; CHEBI:3176; Birnzolamide;Azopt;
  • CAS Registry Number:
  • Flash Point: 308.2 °C
  • Boiling Point: 586 °C at 760mmHg
  • Density: 1.5 g/cm3
  • Flash Point: 308.2 °C
  • Molecular Weight: 383.50724
  • InchiKey: HCRKCZRJWPKOAR-JTQLQIEISA-N
  • InChI: InChI=1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,
    19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,
    17)/t10-/m0/s1
  • Molecular Formula: C12H21N3O5S3
  • Molecular Structure:CAS No:138890-62-7 (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,<br />2-e]thiazine-6-sulfonamide

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138890-62-7 Brinzolamide

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References of (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,
2-e]thiazine-6-sulfonamide
Title: Brinzolamide
CAS Registry Number: 138890-62-7
CAS Name: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
Manufacturers' Codes: AL-4682
Trademarks: Azopt (Alcon)
Molecular Formula: C12H21N3O5S3
Molecular Weight: 383.51
Percent Composition: C 37.58%, H 5.52%, N 10.96%, O 20.86%, S 25.08%
Literature References: Carbonic anhydrase inhibitor. Prepn: T. R. Dean et al., WO 9115486; eidem, US 5378703 (1991, 1995 both to Alcon). Clinical trial: L. H. Silver, Am. J. Ophthalmol. 126, 400 (1998).
Properties: Sol in ethanol.
 
Derivative Type: Hydrochloride
CAS Registry Number: 150937-43-2
Molecular Formula: C12H21N3O5S3.HCl
Molecular Weight: 419.97
Percent Composition: C 34.32%, H 5.28%, N 10.01%, O 19.05%, S 22.91%, Cl 8.44%
Properties: Crystals from methanol + methylene chloride, mp 175-177°. [a]D +10.35° (c = 1 in water).
Melting point: mp 175-177°
Optical Rotation: [a]D +10.35° (c = 1 in water)
 
Therap-Cat: Antiglaucoma agent.
Keywords: Antiglaucoma; Carbonic Anhydrase Inhibitor.