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CAS No 14008-44-7 , 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide Search by region : Denmark

  • Name: 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
  • Synonyms: EINECS 237-818-4; 14008-44-7; EXP 999;1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide; BRN 4278585;Vogalene; RP 9965; Metopimazina [INN-Spanish]; Nortrip; Metopimazinum [INN-Latin];
  • CAS Registry Number:
  • Melting Point: 445.598
  • Flash Point: 390°C
  • Boiling Point: 721.2°Cat760mmHg
  • Density: 1.293g/cm3
  • Refractive index: 1.626
  • Safety Statements: Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. An anti-emetic agent. When heated to decomposition it emits very toxic fumes of SOx and NOx.
  • Flash Point: 390°C
  • EINECS: 237-818-4
  • Molecular Weight: 445.59808
  • InchiKey: BQDBKDMTIJBJLA-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H27N3O3S2/c1-30(27,
    28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-
    14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)
  • Molecular Formula: C22H27N3O3S2
  • Molecular Structure:CAS No:14008-44-7 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide

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14008-44-7 4-Piperidinecarboxamide,1-[3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-

  • Denmark kemikalieimport [Manufacturers]
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  • Fax: + 45 - 4542 3436
  • Address: Lyngby Hovedgade 61.2800 Lyngby. Lyngby,HovedgadeDenmark
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References of 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
Title: Metopimazine
CAS Registry Number: 14008-44-7
CAS Name: 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide
Synonyms: 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide; 10-[3-(4-carbamoylpiperidino)propyl]-2-(methanesulfonyl)phenothiazine; 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]-4-piperidinecarboxamide
Manufacturers' Codes: EXP-999; RP-9965
Trademarks: Vogalene (Thraplix)
Molecular Formula: C22H27N3O3S2
Molecular Weight: 445.60
Percent Composition: C 59.30%, H 6.11%, N 9.43%, O 10.77%, S 14.39%
Literature References: Prepn: Jacob, Robert, DE 1092476 (to Rh?ne-Poulenc), C.A. 56, 8723h (1962). Toxicity study: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Solid, mp 170-171°. LD50 in male rats (mg/kg): 976 orally, 1080 s.c. (Goldenthal).
Melting point: mp 170-171°
Toxicity data: LD50 in male rats (mg/kg): 976 orally, 1080 s.c. (Goldenthal)
Therap-Cat: Antiemetic.
Keywords: Antiemetic.