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CAS No 1401-69-0 , Tylosin Search by region : China

  • Name: Tylosin
  • Synonyms: Tylosin base;Tylosin;
  • CAS Registry Number:
  • Flash Point: 546.9°C
  • Boiling Point: 980.7°Cat760mmHg
  • Density: 1.24g/cm3
  • Refractive index: 1.548
  • Water Solubility: soluble in water, micro-soluble in alcohol, ketone and ester
  • Safety Statements: 36
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 546.9°C
  • EINECS: 215-754-8
  • Molecular Weight: 916.10
  • InChI: InChI=1/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25?,26-,27-,28+,29+,30?,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45?,46-/m1/s1
  • Risk Statements: 42/43
  • Molecular Formula: C46H77NO17
  • Molecular Structure:CAS No:1401-69-0 Tylosin

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1401-69-0 Tylosin

  • China Sinobright Pharmaceutical Co., Ltd. [Trading Company]
  • Tel: 86-0755-26974357
  • Address: 503 Zhongguan Building, Liuxian Road, Nanshan District, Shenzhen, China shenzhen,GuangdongChina
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1401-69-0 TYLOSIN

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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1401-69-0 TYLOSIN

  • China HANGZHOU ONICON CHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-571-85054016/ +86-571-85104679
  • Fax: +86-571-85054082
  • Address: HANGZHOU ONICON CHEMICAL CO.,LTD
    303-306 Hangzhou yiyao Building,
    No.439 Zhongshan North Rd.
    Hangzhou China
    Phone : +86-571-85054016
    Fax: +86-571-85054082
    E-Mail1: cjw9999@163.com null,nullChina
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1401-69-0 TYLOSIN

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1401-69-0 tylosin

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1401-69-0 Tylosin base

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1401-69-0 TYLOSIN

  • China Ancheng Pharma Limited [Manufacturers]
  • Tel: +86-755-82713308
  • Fax: 0086-755-82713413
  • Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China Shenzhen,guangdongChina
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1401-69-0 Tylosin

  • China Shanghai Mingdou Chemical Co.,Ltd [Manufacturers]
  • Tel: 86-21-52912919
  • Fax: 021-52912097
  • Address: Floor 12th, Zhenyuan Building ,No 2052.North Zhongshan Road, Shanghai,China null,shanghaiChina
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1401-69-0 Tylosin base

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1401-69-0 Tylosin

  • China Saniver Limited null
  • Fax: +86-21-62882088 +86-852-23333065
  • Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong. null,nullChina
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References of Tylosin
Title: Tylosin
CAS Registry Number: 1401-69-0
Trademarks: Tylan (Elanco)
Molecular Formula: C46H77NO17
Molecular Weight: 916.10
Percent Composition: C 60.31%, H 8.47%, N 1.53%, O 29.69%
Literature References: Macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand: Hamill et al., Antibiot. Chemother. 11, 328 (1961); eidem, US 3178341 (1965 to Lilly). Prodn in batch and chemostat cultures: P. P. Gray, S. Bhuwapathanapun, Biotechnol. Bioeng. 22, 1785 (1980). Partial structure: Morin, Gorman, Tetrahedron Lett. 1964, 2339. Structure: Morin et al., ibid. 1970, 4737; Achenbach et al., Ber. 108, 2481 (1975). Configurational study: S. Omura et al., Tetrahedron Lett. 1977, 1045. Abs config: eidem, J. Antibiot. 33, 915 (1980); N. D. Jones et al., ibid. 35, 420 (1982). Synthesis of tylonolide, the aglycone: S. Masamune et al., J. Am. Chem. Soc. 98, 7874 (1976); K. Tatsuta et al., Tetrahedron Lett. 22, 3997 (1981). Relationship of ribosomal binding and antibacterial properties: J. W. Corcoran et al., J. Antibiot. 30, 1012 (1977). Biosynthesis studies: E. T. Seno et al., Antimicrob. Agents Chemother. 11, 455 (1977); S. Omura et al., J. Antibiot. 31, 254 (1978).
Properties: Crystals from water, mp 128-132°. [a]D25 -46° (c = 2 in methanol). uv max: 282 nm (E1%1cm 245). Soly in water at 25°: 5 mg/ml. Sol in lower alcohols, esters and ketones, in chlorinated hydrocarbons, benzene, ether. Solns are stable at pH 4-9; at pH <4 another active compd, desmycosin is formed.
Melting point: mp 128-132°
Optical Rotation: [a]D25 -46° (c = 2 in methanol)
Absorption maximum: uv max: 282 nm (E1%1cm 245)
 
Derivative Type: Hydrochloride
Molecular Formula: C46H77NO17.HCl
Molecular Weight: 952.56
Percent Composition: C 58.00%, H 8.25%, N 1.47%, O 28.55%, Cl 3.72%
Properties: Crystals from ethanol + ether, mp 141-145°.
Melting point: mp 141-145°
 
Therap-Cat-Vet: Antibacterial.