Home > Name List By 2 > 2-amino-9-[(1S,3R, 4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one China

CAS No 142217-69-4 , 2-amino-9-[(1S,3R,
4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one Search by region : China

  • Name: 2-amino-9-[(1S,3R,
    4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
  • Synonyms: BMS-200475;2-amino-9-[(1S,3R,
    4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one; Entecavir (INN); 142217-69-4; CHEMBL713;Baraclude; AC1L4BEC; MolPort-005-942-963; CHEBI:473990; SQ-34676;
  • CAS Registry Number:
  • Density: 1.81g/cm3
  • Refractive index: 1.837
  • Molecular Weight: 277.2792
  • InchiKey: QDGZDCVAUDNJFG-FXQIFTODSA-N
  • InChI: InChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-
    11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1
  • Molecular Formula: C12H15N5O3
  • Molecular Structure:CAS No:142217-69-4 2-amino-9-[(1S,3R,<br />4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one

Select to

142217-69-4 Entecavir

  • Entecavir Chemical Properties Melting point 249-252°C Boiling point 661.4±65.0 °C(Predicted) density 1.81±0.1 g/cm3(Predicted) storage temp. -20°C Freezer form powder pka 14.22±0.60(Predicted) color white to beige optical activity [α]/D +25 to +40°,...
  • Min. Order: 100
  • China shanghai missyou chemical co.,ltd. [Manufacturer]
  • Tel: 86-21-58583907
  • Address: NO 3668,Tingwei ROad Jinshan Area, shanghai,ShanghaiChina
Contact Supplier

142217-69-4 Entecavir

  • Product Name: Entecavir Synonyms: ENTECAVIR;Entecavi;ENTECAVIR, 98-102%;entecavir Baraclude;2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one, Baraclude;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-me...
  • Min. Order: 500
  • FOB Price: USD0.5 - 1 /
  • China Wuhan Hezhong Bio-Chemical Manufature Co.,Ltd [Manufacturer]
  • Tel: 86-27-50756046
  • Address: Zhongshan Road No 496 Wuhan,HubeiChina
Contact Supplier

142217-69-4 Entecavir

  • Product Name: Entecavir Synonyms: ENTECAVIR;Entecavi;ENTECAVIR, 98-102%;entecavir Baraclude;2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one, Baraclude;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-me...
  • Min. Order: 500
  • FOB Price: USD0.5 - 1 /
  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd. [Manufacturer]
  • Tel: 86-27-50756064
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
Contact Supplier

142217-69-4 2-amino-9-[(1S,3R, 4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one

  • Company has built a high standard R&D center which equipped first-class research instruments. The center includes synthesis laboratory, analytical laboratory, applied research laboratory. We also gathered a group of technical talents who were from ho...
  • China Novtect Limited Company [Manufacturer, Distributor/Wholesaler, Government ministry/Bureau/Commission]
  • Tel: 86-010-57297856
  • Fax: 86-010-57815012
  • Address: Building D-3, Zhongguancun Dongsheng Science Park, No. 66 Xixiaokou Road, Haidian District , Beijing,nullChina

142217-69-4 Entecavir

  • As you know, we make sure our products' quality. The details pls find enclosed 'Certificate of Analysis' once your reply (Email/Fax/Phone) for your enquiry received. The price can be consulted upon your counteroffer for quality together with quantity...
  • Min. Order: 10
  • China Chemda Pha ma Chemical Co., LTD [Manufacturer]
  • Tel: 86-0-18360693208
  • Fax: 86-518-85687072
  • Address: No.1209, 12 Building, Huaihai Industrial Institute S&T Park, China Lianyungang,JiangsuChina

142217-69-4 entecavir

  • China Shanghai Yingxuan Chempharm Co., Ltd. [Manufacturer]
  • Tel: 86-21-50323911
  • Fax: 86-21-50323911
  • Address: Shanghai Yingxuan Chempharm Co., Ltd.
    No.1-303, 666 Taierzhuang Rd.,
    Pudong, Shanghai,
    CN-201206,China null,nullChina
Contact Supplier

142217-69-4 ENTECAVIR

  • China Simag Chemicals [Manufacturer]
  • Tel: +86 592 2680277
  • Fax: +86 592 2680237
  • Address: Simag Chemicals
    A-9D Atlantic sea view city,
    No.9 Hubin West Rd.,
    Xiamen China. null,nullChina
Contact Supplier

142217-69-4 Entecavir CAS NO.:142217-69-4

Contact Supplier

142217-69-4 Entecavir

  • Entecavir, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
Contact Supplier

142217-69-4 Entecavir

  • FOB Price: RMB500000 - 600000 /
  • China Bejing Alliesyn Technology Co.,Ltd [Manufacturer]
  • Tel: 86-10-52461006
  • Address: 4/F,Yunlongyiran Building,No.77 South Gucheng Avenue,Shijingshan District Beijing,BeijingChina
Contact Supplier

Select to

References of 2-amino-9-[(1S,3R,
4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
Title: Entecavir
CAS Registry Number: 142217-69-4
CAS Name: 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
Molecular Formula: C12H15N5O3
Molecular Weight: 277.28
Percent Composition: C 51.98%, H 5.45%, N 25.26%, O 17.31%
Literature References: Deoxyguanine nucleoside analog; inhibits hepatitis B virus (HBV) DNA polymerase. Prepn: R. Zahler, W. A. Slusarchyk, EP 481754; eidem, US 5206244 (1992, 1993 both to Squibb); G. S. Bisacchi et al., Bioorg. Med. Chem. Lett. 7, 127 (1997). In vitro antiviral activity: S. F. Innaimo et al, Antimicrob. Agents Chemother. 41, 1444 (1997). Review of pharmacology and clinical experience: P. Honkoop, R. A. de Man, Expert Opin. Invest. Drugs 12, 683-688 (2003); T. Shaw, S. Locarnini, Expert Rev. Anti Infect. Ther. 2, 853-871 (2004). Clinical comparisons with lamivudine in chronic hepatitis B: T.-T. Chang et al., N. Engl. J. Med. 354, 1001 (2006); C.-L. Lai et al., ibid. 1011.
 
Derivative Type: Monohydrate
CAS Registry Number: 209216-23-9
Manufacturers' Codes: BMS-200475; SQ-200475
Trademarks: Baraclude (BMS)
Molecular Formula: C12H15N5O3.H2O
Molecular Weight: 295.29
Percent Composition: C 48.81%, H 5.80%, N 23.72%, O 21.67%
Properties: White to off-white powder, mp >220°. [a]D +35.0° (c = 0.38 in water). Soly in water: 2.4 mg/ml. pH of saturated soln in water is 7.9 at 25°±0.5°.
Melting point: mp >220°
Optical Rotation: [a]D +35.0° (c = 0.38 in water)
 
Therap-Cat: Antiviral.
Keywords: Antiviral; Purines/Pyrimidinones.