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CAS No 1477-19-6 , (2-ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone

  • Name: (2-ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone
  • Synonyms: Fragivil; Fagivil;Benzaron;(2-ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone; Venagil; Benzaronum [INN-Latin]; Vasoc; 1477-19-6; 2-Ethyl-3-(4-hydroxybenzoyl)benzofuran; Fragivix;
  • CAS Registry Number:
  • Flash Point: 240.2°C
  • Boiling Point: 473.6°Cat760mmHg
  • Density: 1.234g/cm3
  • Refractive index: 1.638
  • Safety Statements: Poison by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. A flammable liquid. When heated to decomposition it emits acrid and irritating smoke and fumes. See also KETONES.
  • Flash Point: 240.2°C
  • EINECS: 216-026-2
  • Molecular Weight: 266.29126
  • InchiKey: RFRXIWQYSOIBDI-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H14O3/c1-2-14-16(13-5-3-4-6-15(13)20-14)17(19)11-7-9-12(18)
    10-8-11/h3-10,18H,2H2,1H3
  • Molecular Formula: C17H14O3
  • Molecular Structure:CAS No:1477-19-6 (2-ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone

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1477-19-6 BENZARONE

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1477-19-6 Benzarone

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References of (2-ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone
Title: Benzarone
CAS Registry Number: 1477-19-6
CAS Name: (2-Ethyl-3-benzofuranyl)(4-hydroxyphenyl)methanone
Synonyms: 2-ethyl-3-benzofuranyl p-hydroxyphenyl ketone; 2-ethyl-3-(4-hydroxybenzoyl)benzofuran; 2-ethyl-3-(p-hydroxybenzoyl)coumarone
Manufacturers' Codes: L-2197
Trademarks: Fragivix (Sanofi Winthrop); Vasoc (Lindopharm)
Molecular Formula: C17H14O3
Molecular Weight: 266.29
Percent Composition: C 76.68%, H 5.30%, O 18.02%
Literature References: Prepn: Buu-Hoi, Beaudet, US 3012042 (1961 to Soc. Belge l'Azote Prod. Chim. Marly). Pharmacological studies: Barchewitz et al., Arzneim.-Forsch. 22, 553 (1972). Site of action studies: I. Filipovic, E. Buddecke, ibid. 29, 1578 (1979); L. O. Zwillenberg et al., ibid. 32, 1114 (1982). HPLC determination in serum: H. Vergin, G. Bishop, J. Chromatogr. 183, 383 (1980).
Properties: Crystals, mp 124.3°.
Melting point: mp 124.3°
Therap-Cat: Capillary protectant.
Keywords: Vasoprotectant.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.