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CAS No 1508-75-4 , N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide

  • Name: N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
  • Synonyms: Ocu-Tropic; 1508-75-4;N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide; Paremyd;Tropicacyl; Mydrum; Minims tropicamide; Mydriafair; Mydriacyl; Mydriaticum;
  • CAS Registry Number:
  • Melting Point: 98 °C
  • Flash Point: 251.8°C
  • Boiling Point: 492.8°Cat760mmHg
  • Density: 1.161g/cm3
  • Refractive index: 1.586
  • Safety Statements: R20/21/22;R36/37/38;R42/43
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 251.8°C
  • EINECS: 216-140-2
  • Molecular Weight: 284.3529
  • InchiKey: BGDKAVGWHJFAGW-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-
    3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
  • Risk Statements: S22;S26;S36
  • Molecular Formula: C17H20N2O2
  • Molecular Structure:CAS No:1508-75-4 N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide

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  • Tropicamide
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References of N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
Title: Tropicamide
CAS Registry Number: 1508-75-4
CAS Name: N-Ethyl-a-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide
Synonyms: N-ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide; N-ethyl-N-(g-picolyl)tropamide
Trademarks: Mydriacyl (Alcon); Mydriaticum (Merck & Co.)
Molecular Formula: C17H20N2O2
Molecular Weight: 284.35
Percent Composition: C 71.81%, H 7.09%, N 9.85%, O 11.25%
Literature References: Ophthalmic anticholinergic. Prepn: Rey-Bellet, Spiegelberg, US 2726245 (1955 to Hoffmann-La Roche). Comprehensive description: K. W. Blessel et al., Anal. Profiles Drug Subs. 3, 565-580 (1974).
Properties: Crystals, mp 96-97°. uv max (0.025 mg/ml in 0.1N HCl): 254 nm (e 5.1′103).
Melting point: mp 96-97°
Absorption maximum: uv max (0.025 mg/ml in 0.1N HCl): 254 nm (e 5.1′103)
Therap-Cat: Mydriatic.
Therap-Cat-Vet: Mydriatic.
Keywords: Antimuscarinic; Mydriatic.