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CAS No 15291-75-5 , Ginkgolide A Search by region : China

  • Name: Ginkgolide A
  • Synonyms: Ginkgolide A;-;
  • CAS Registry Number:
  • Density: 1.56 g/cm3
  • Refractive index: 1.631
  • Molecular Weight: 408.40
  • InChI: InChI=1/C20H24O9/c1-7-12(22)26-10-6-17-9-5-8(16(2,3)4)18(17)11(21)13(23)28-15(18)29-20(17,14(24)27-9)19(7,10)25/h7-11,15,21,25H,5-6H2,1-4H3/t7-,8+,9-,10+,11+,15+,17?,18?,19-,20?/m1/s1
  • Molecular Formula: C20H24O9
  • Molecular Structure:CAS No:15291-75-5 Ginkgolide A

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15291-75-5 Ginkgolide A

  • English Name: Ginkgolide A English Nickname: Molecular Formula: C20H24O9 Molecular Weight: 408.40 CAS: 15291-75-5 Purity: HPLC≥98% Package: 10g 20g 50g 100g, or customized. Appearance: White crystal Source: Fructification of GinkgobilobaL. Solubilit...
  • Min. Order: 0
  • China Sichuan Weikeqi Biological Technology Co., Ltd [Other]
  • Tel: 86-028-81700200
  • Fax: 86-028-81705658
  • Address: Qingjiang Zhonglu 63 chengdu,SichuanChina

15291-75-5 ginkgolide A

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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15291-75-5 Ginkgolide A

  • Ginkgolide A
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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15291-75-5 Ginkgolide A

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15291-75-5 Ginkgolide A

  • Ginkgolide A1,7-Dideoxyginkgolide C
  • China Beijing HuameiHuli Biochem Ltd [Manufacturers]
  • Tel: 010-86181995
  • Fax: 010-86860610
  • Address: Beijing TongZhou District Beijing,BeijingChina
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15291-75-5 Ginkgolide A

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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15291-75-5 ginkgolide A

  • China BioBioPha Co., Ltd. [Manufacturer]
  • Tel: +86-871-5217109
  • Fax: +86-871-5217109
  • Address: 132 Lanhei Road, Kunming Institute of Botany, Chinese Academy of Sciences null,nullChina
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15291-75-5 Ginkgolide A

  • Ginkgolide A, 98%
  • China Aktin Chemicals, Inc. [Manufacturer]
  • Tel: +86-28-85159085
  • Fax: +86-28-85152372
  • Address: Aktin Chemicals, Inc.
    Yongfeng Plaza, No.52,
    Yongfeng Road, Hi-tech Zone,
    Chengdu 610041
    P.R.China null,nullChina
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15291-75-5 Ginkgolide A

  • China Shanghai Howson Biotech Co.,Ltd. [Manufacturer]
  • Tel: +86-21-622-77841
  • Fax: +86-21-62277840
  • Address: B-7C, 1068, Xikang Road,
    Shanghai,China 200060 null,nullChina
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15291-75-5 ginkgolide A

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References of Ginkgolide A
Title: Ginkgolides
Literature References: Family of bioactive terpenes isolated from the root bark and leaves of Ginkgo biloba L., Ginkgoaceae. Specific platelet activating factor (PAF) antagonists. Isoln from leaves: S. Furukawa, Sci. Papers Inst. Phys. Chem. Res. Jpn. 19, 27 (1932), C.A. 27, 303 (1933). Isoln from root bark and characterization: M. Maruyama et al., Tetrahedron Lett. 1967, 299; K. Nakanishi, Pure Appl. Chem. 14, 89 (1967); from leaves: N. Sakabe et al., Chem. Commun. 1967, 259; K. Okabe et al., J. Chem. Soc. C 1967, 2201. Crystal structure of B: L. Dupont et al., Acta Crystallogr. C42, 1759 (1986); of A and C: M. Sbit et al., ibid. C43, 2377 (1987). Total synthesis of (±)-B: E. J. Corey et al., J. Am. Chem. Soc. 110, 649 (1988); of (±)-A: E. J. Corey, A. K. Ghosh, Tetrahedron Lett. 29, 3205 (1988). Enantioselective route to B: E. J. Corey, A. V. Gavai, ibid., 3201. Review of syntheses: E. J. Corey, Chem. Soc. Rev. 17, 111-133 (1988). 1H- and 13C-NMR: C. Roumestand et al., Tetrahedron 45, 1975 (1989). Effect on PAF receptor binding: R. Korth et al., Eur. J. Pharmacol. 152, 101 (1988). Review: P. Braquet et al., Med. Res. Rev. 11, 295-355 (1991). Review of physical properties: T. A. van Beek, Bioorg. Med. Chem. 13, 5001-5012 (2005).
Properties: Ginkgolides are sol in acetone, ethanol, methanol, ethyl acetate, THF, dioxane, acetic acid, trifluoroacetic acid, acetonitrile, pyridine, DMSO; sparingly sol in ether, water. Insol in hexane, benzene, chloroform, carbon tetrachloride.
 
Derivative Type: Ginkgolide A
CAS Registry Number: 15291-75-5
Manufacturers' Codes: BN-52020
Molecular Formula: C20H24O9
Molecular Weight: 408.40
Percent Composition: C 58.82%, H 5.92%, O 35.26%
Properties: Bitter crystals from ethanol, mp ~300° (dec). [a]D24 -53.4° (c = 1 in ethanol). uv max (ethanol): 219 nm (log e 2.72).
Melting point: mp ~300° (dec)
Optical Rotation: [a]D24 -53.4° (c = 1 in ethanol)
Absorption maximum: uv max (ethanol): 219 nm (log e 2.72)
 
Derivative Type: Ginkgolide B
CAS Registry Number: 15291-77-7
CAS Name: (1b)-1-Hydroxyginkgolide A
Manufacturers' Codes: BN-52021
Molecular Formula: C20H24O10
Molecular Weight: 424.40
Percent Composition: C 56.60%, H 5.70%, O 37.70%
Literature References: Review of pharmacology and PAF-antagonism: P. Braquet, R. H. Bourgain, Adv. Exp. Med. Biol. 215, 215-235 (1987). Clinical trial in asthma: K.-H. Hsieh, Chest 99, 877 (1991); in severe sepsis: J. F. Dhainaut et al., Crit. Care Med. 22, 1720 (1994).
Properties: Bitter crystals from ethanol, mp ~300° (dec). [a]D24 -52.6° (c = 1 in ethanol). uv max (ethanol): 219 nm (log e 2.37). Log P (water/n-octanol): 1.72. pKa1 7.14; pKa2 8.60; pKa3 11.89.
Melting point: mp ~300° (dec)
pKa: pKa1 7.14; pKa2 8.60; pKa3 11.89
Optical Rotation: [a]D24 -52.6° (c = 1 in ethanol)
Log P: Log P (water/n-octanol): 1.72
Absorption maximum: uv max (ethanol): 219 nm (log e 2.37)
 
Derivative Type: Ginkgolide C
CAS Registry Number: 15291-76-6
CAS Name: (1a,7b)-1,7-Dihydroxyginkgolide A
Manufacturers' Codes: BN-52022
Molecular Formula: C20H24O11
Molecular Weight: 440.40
Percent Composition: C 54.54%, H 5.49%, O 39.96%
Properties: Bitter crystals from ethanol, mp ~300° (dec). [a]D24 -14.7° (c = 1 in ethanol). uv max (ethanol): 220 nm (log e 2.30).
Melting point: mp ~300° (dec)
Optical Rotation: [a]D24 -14.7° (c = 1 in ethanol)
Absorption maximum: uv max (ethanol): 220 nm (log e 2.30)
 
Use: Reference compd for PAF receptors in biological systems.