Home > Name List By 3 > 3-[3,5-dimethyl-4-[3-(3-methyl-1, 2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole Germany

CAS No 153168-05-9 , 3-[3,5-dimethyl-4-[3-(3-methyl-1,
2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole Search by region : Germany

  • Name: 3-[3,5-dimethyl-4-[3-(3-methyl-1,
    2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
  • Synonyms: 3-{3,5-dimethyl-4-[3-(3-methyl-isoxazol-5-yl)-propoxy]-phenyl}-5-trifluoromethyl-[1,2,4]oxadiazole;3-[3,5-dimethyl-4-[3-(3-methyl-1,
    2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole; VP-63843; Picovir;Pleconaril; Win-63843;
  • CAS Registry Number:
  • Flash Point: 244.8°C
  • Boiling Point: 481.2°Cat760mmHg
  • Density: 1.271
  • Refractive index: 1.509
  • Flash Point: 244.8°C
  • Molecular Weight: 381.34903
  • InchiKey: KQOXLKOJHVFTRN-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H18F3N3O3/c1-10-7-13(16-22-17(27-24-16)18(19,
    20)21)8-11(2)15(10)25-6-4-5-14-9-12(3)23-26-14/h7-9H,4-6H2,1-3H3
  • Molecular Formula: C18H18F3N3O3
  • Molecular Structure:CAS No:153168-05-9 3-[3,5-dimethyl-4-[3-(3-methyl-1,<br />2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole

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153168-05-9 pleconaril

  • pleconaril
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
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References of 3-[3,5-dimethyl-4-[3-(3-methyl-1,
2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
Title: Pleconaril
CAS Registry Number: 153168-05-9
CAS Name: 3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
Synonyms: 5-[3-[2,6-dimethyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy]propyl]-3-methylisoxazole
Manufacturers' Codes: VP-63843; Win-63843
Molecular Formula: C18H18F3N3O3
Molecular Weight: 381.35
Percent Composition: C 56.69%, H 4.76%, F 14.95%, N 11.02%, O 12.59%
Literature References: Picornavirus replication inhibitor. Prepn: G. D. Diana, T. J. Nitz, EP 566199; eidem, US 5464848 (1993, 1995 both to Sterling Winthrop). Stability and HPLC determn of degradation products: A. B. C. Yu et al., Drug Dev. Ind. Pharm. 21, 1827 (1995). Activity spectrum vs enteroviruses: D. C. Pevear et al., Antimicrob. Agents Chemother. 43, 2109 (1999). Clinical pharmacokinetics in children: G. L. Kearns et al., ibid. 634; in adults: S. M. Abdel-Rahman, G. L. Kearns, J. Clin. Pharmacol. 39, 613 (1999). Clinical trial in induced respiratory infection: G. M. Schiff, J. R. Sherwood, J. Infect. Dis. 181, 20 (2000).
Properties: White solid, mp 61-62°. Soly at 25° (ng/ml): water < 20. Sol in safflower seed oil, corn oil or corn oil-ethanol solutions.
Melting point: mp 61-62°
Therap-Cat: Antiviral.
Keywords: Antiviral.