Home > Name List By 5 > 5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide

CAS No 168273-06-1 , 5-(4-chlorophenyl)-1-(2,
4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide

  • Name: 5-(4-chlorophenyl)-1-(2,
    4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
  • Synonyms: Slimona; Zimulti; 168273-06-1; Rimoslim; SR141716A;5-(4-chlorophenyl)-1-(2,
    4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide; SR 141716; SR141716; Riobant;Acomplia;
  • CAS Registry Number:
  • Density: 1.41g/cm3
  • Refractive index: 1.668
  • Molecular Weight: 463.78734
  • InchiKey: JZCPYUJPEARBJL-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-
    17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,
    (H,27,30)
  • Molecular Formula: C22H21Cl3N4O
  • Molecular Structure:CAS No:168273-06-1 5-(4-chlorophenyl)-1-(2,<br />4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
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168273-06-1 1H-Pyrazole-3-carboxamide,5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-

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168273-06-1; 158681-13-1 Rimonabant

  • China Levachem Co. Ltd. [Manufacturers]
  • Tel: 86-25-83247442 / 443 / 445 / 446 / 447
  • Fax: +86-25-83247441
  • Address: 2112, SuNing Universal Mansion, 188 Guangzhou Road, Nanjing-210024, China Nanjing,jiangsuChina
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168273-06-1 1H-Pyrazole-3-carboxamide,5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-

  • China Beyond Pharmatech Corp, Ltd [Manufacturer, Agent]
  • Tel: +86-157-2497-1806
  • Fax: +86-571-5811-0575
  • Address: XiangYuan Road, GongShu District, Hangzhou, ZheJiang, 310011, China hangzhou,zhejiangChina
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168273-06-1 1H-Pyrazole-3-carboxamide,5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-

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168273-06-1; 158681-13-1 Rimonabant

  • China IFFECT CHEMPHAR CO., LTD. null
  • Tel: 0086 755-83761619 83760606
  • Fax: +86-25- 84270111
  • Address: 15A,Changfa Center, Building B ,No. 300,East Zhongshan Road,Baixia District,Nanjing,210002, P.R.China. Nanjing,JiangshuChina
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168273-06-1; 158681-13-1 Rimonabant

  • China Hwasun Biotechnology Co., Ltd. null
  • Fax: 86-21-64765024
  • Address: Rm.505, Bldg. 2,No. 245 Jiachuan RD. Xuhui Dist.,200237, Shanghai, China null,nullChina
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168273-06-1 1H-Pyrazole-3-carboxamide,5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-

  • China EASYBUYER LTD., [Manufacturers]
  • Tel: +86-21-35015877 +86-13701868511
  • Fax: +86-21-35010877
  • Address: Room 407, Building 10, Hi-Shanghai Center, No.990 Dalian Rd,Shanghai 200092 China null,ShanghaiChina
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168273-06-1 1H-Pyrazole-3-carboxamide,5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-

  • China GreatAp Chemicals Co.Ltd. [Manufacturers]
  • Tel: 86-316-2098955,6896679
  • Fax: 86-316-2098956
  • Address: No.89,Xinhua Road, Langfang City,Hebei China null,HebeiChina
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168273-06-1; 158681-13-1 RIMONABANT

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168273-06-1; 158681-13-1 Rimonabant

  • China Rota Pharm and Chem Co., Ltd. null
  • Fax: +86-571-87918114
  • Address: Room 401,Hangzhou Friendship Plaza,No.74 Bbaochu Road, Hangzhou, China null,nullChina
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References of 5-(4-chlorophenyl)-1-(2,
4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
Title: Rimonabant
CAS Registry Number: 168273-06-1
CAS Name: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
Synonyms: N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
Manufacturers' Codes: SR-141716
Trademarks: Acomplia (Sanofi-Synthelabo)
Molecular Formula: C22H21Cl3N4O
Molecular Weight: 463.79
Percent Composition: C 56.97%, H 4.56%, Cl 22.93%, N 12.08%, O 3.45%
Literature References: Brain cannabinoid receptor (CB1) antagonist. Prepn: F. Barth et al., EP 576357; eidem., US 5624941 (1993, 1997 both to Sanofi); H. H. Seltzman et al., J. Chem. Soc. Chem. Commun. 1995, 1549; and pharmacology: A. K. Dutta et al., Med. Chem. Res. 5, 54 (1994). Receptor antagonist activity: M. Rinaldi-Carmona et al., FEBS Lett. 350, 240 (1994). Clinical trial in blockade of effects of smoked marijuana: M. A. Huestis et al., Arch. Gen. Psychiatry 58, 322 (2001). Clinical trials in obesity: L. F. Van Gaal et al., Lancet 365, 1389 (2005); J.-P. Després et al., N. Engl. J. Med. 353, 2121 (2005). Review of therapeutic potential in obesity and drug addiction: M. A. M. Carai et al., Life Sci. 77, 2339-2350 (2005).
 
Derivative Type: Hydrochloride
CAS Registry Number: 158681-13-1
Manufacturers' Codes: SR-141716A
Molecular Formula: C22H21Cl3N4O.HCl
Molecular Weight: 500.25
Percent Composition: C 52.82%, H 4.43%, Cl 28.35%, N 11.20%, O 3.20%
Properties: White crystals from ether + petr ether, mp 154-156° (Dutta); also reported as mp 157-159° (Seltzman).
Melting point: mp 154-156° (Dutta); mp 157-159° (Seltzman)
 
Therap-Cat: Antiobesity agent.
Keywords: Antiobesity Agent.