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CAS No 171596-29-5 , Cialis

  • Name: Cialis
  • Synonyms: Tadanafil; ICOS 351; Ic351; IC-351; ADCIRCA; 1xoz; IC 351; 171596-29-5;Cialis;
  • CAS Registry Number:
  • Flash Point: 364.5ºC
  • Boiling Point: 679.1ºC at 760 mmHg
  • Density: 1.51 g/cm3
  • Refractive index: 1.705
  • Safety Statements: The most common side effects of tadalafil are: are headache, indigestion, flushing,back pain, muscle aches and stuffy or runny nose. These side effects reflect the ability of PDE5 inhibition to vasodilate (cause blood vessels to widen), these usually go a
  • Flash Point: 364.5ºC
  • Molecular Weight: 389.40396
  • InchiKey: WOXKDUGGOYFFRN-IIBYNOLFSA-N
  • InChI: InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)
    23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,
    1H3/t16-,21-/m1/s1
  • Molecular Formula: C22H19N3O4
  • Molecular Structure:CAS No:171596-29-5 Cialis

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  • Tadalafil CAS NO.: 171596-29-5 Assay: 99% Molecular Formula:C22H19N3O4 Molecular Weight:389.341 Quality standard: USP31/BP2005 Description: White Crystalline Powder Storage: Shading, Confined Preservation
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    • Tadalafil Chemical Name: Cialis Synonyms: IC 351;CIALIS;ICOS 351;TADALAFIL CAS No: 171596-29-5 Molecular Formula: C22H19N3O4 Molecular Weight: 389.341 Purity: 99% Assay:99% Melting point 140-144 °C EINECS 259-415-2 Packing: 1kg/bag Quality standard: ...
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    171596-29-5 Tadalafil

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    References of Cialis
    Title: Tadalafil
    CAS Registry Number: 171596-29-5
    CAS Name: (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1¢,2¢:1,6]pyrido[3,4-b]indole-1,4-dione
    Synonyms: (6R,12aR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-[3,4-(methylenedioxy)phenyl]pyrazino[1¢,2¢:1,6]pyrido[3,4-b]indole-1,4-dione
    Manufacturers' Codes: GF-196960; IC-351
    Trademarks: Cialis (Lilly)
    Molecular Formula: C22H19N3O4
    Molecular Weight: 389.40
    Percent Composition: C 67.86%, H 4.92%, N 10.79%, O 16.43%
    Literature References: Selective type 5 cGMP phosphodiesterase (PDE-5) inhibitor. Prepn: A. C. Daugan, WO 9519978 (1995 to Glaxo); eidem, US 5859006 (1999 to ICOS); and PDE-5 inhibition: idem et al., J. Med. Chem. 46, 4525, 4533 (2003). HPLC determn in plasma: C.-L. Cheng, C.-H. Chou, J. Chromatogr. B 822, 278 (2005). Clinical pharmacokinetics: S. T. Forgue et al., Br. J. Clin. Pharmacol. 61, 280 (2005). Clinical trial in erectile dysfunction: G. B. Brock et al., J. Urol. 168, 1332 (2002); in comparison with sildenafil: I. Eardley et al., BJU Int. 96, 1323 (2005). Review of pharmacology and clinical experience: H. Porst, Int. J. Impotence Res. 14, Suppl. 1, S57-S64 (2002); in comparison with other phosphodiesterase inhibitors: S. A. Doggrell, Expert Opin. Pharmacother. 6, 75-84 (2005).
    Properties: White crystals from 2-propanol, mp 302-303°. [a]D20 +71.0° (c = 1.00 in CHCl3). Very slightly sol in ethanol. Practically insol in water.
    Melting point: mp 302-303°
    Optical Rotation: [a]D20 +71.0°
    Therap-Cat: In treatment of male erectile dysfunction.
    Keywords: Impotence Therapy; Phosphodiesterase Inhibitor.