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CAS No 17969-20-9 , 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid Search by region : Ukraine

  • Name: 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid
  • Synonyms: Myalex; 17969-20-9; Acidum fenclozicum;Mialex;2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid; [2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid; Acido fenclozico [Italian];
  • CAS Registry Number:
  • Melting Point: 150-152°C
  • Flash Point: 222.8°C
  • Boiling Point: 444.7°Cat760mmHg
  • Density: 1.434g/cm3
  • Safety Statements: Poison by ingestion, intraperitoneal, and intravenous routes. Experimental reproductive effects. An anti-inflammatory agent. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and SOx.
  • Flash Point: 222.8°C
  • Molecular Weight: 253.70472
  • InchiKey: APBSKHYXXKHJFK-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H8ClNO2S/c12-8-3-1-7(2-4-8)11-13-9(6-16-11)5-10(14)15/h1-4,
    6H,5H2,(H,14,15)
  • Molecular Formula: C11H8ClNO2S
  • Molecular Structure:CAS No:17969-20-9 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid

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17969-20-9 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid

  • 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid chlorophenylthiazolylaceticacid [2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid Fenclozic acid
  • Ukraine Otava Chemicals [Manufacturer]
  • Tel: +380 44 5222458
  • Fax: +380 44 5222458
  • Address: PO 8803187 Kyiv 187UKRAINE 03187 Kyiv 187,nullUkraine
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References of 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid
Title: Fenclozic Acid
CAS Registry Number: 17969-20-9
CAS Name: 2-(4-Chlorophenyl)-4-thiazoleacetic acid
Synonyms: 2-(p-chlorophenyl)thiazol-4-ylacetic acid; acidum fenclozicum
Manufacturers' Codes: ICI-54450
Trademarks: Myalex (ICI)
Molecular Formula: C11H8ClNO2S
Molecular Weight: 253.70
Percent Composition: C 52.08%, H 3.18%, Cl 13.97%, N 5.52%, O 12.61%, S 12.64%
Literature References: Prepn: W. Hepworth, G. J. Stacey, NL 6614130; eidem, US 3538107 (1967, 1970 both to ICI); Aries, FR 1561433 (1969), C.A. 72, 43654y (1970). Pharmacology: W. Hepworth et al., Nature 221, 582 (1969); Newbould, Br. J. Pharmacol. 35, 487 (1969). Metabolic studies: Foulkes, J. Pharmacol. Exp. Ther. 172, 115, 449 (1970). Clinical evaluation: Chalmers et al., Ann. Rheum. Dis. 28, 590, 595 (1969).
Properties: Colorless crystalline solid from ethyl acetate, mp 155-156°. Soluble in most organic solvents; sparingly sol in water. LD50 in rats, mice (mg/kg): 850, 1000 orally; 250, 300 i.v. (Hepworth).
Melting point: mp 155-156°
Toxicity data: LD50 in rats, mice (mg/kg): 850, 1000 orally; 250, 300 i.v. (Hepworth)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives.