Home > Name List By other > (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11, 17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15, 1...

CAS No 2135-17-3 , (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
16-octahydrocyclopenta[a]phenanthren-3-one

  • Name: (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthren-3-one
  • Synonyms: Flumetasone; Flumethason; Flucorticin; Fluvet; Anaprime; Aniprime; Flumetasona; Methagon; Cortexilar;(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthren-3-one;
  • CAS Registry Number:
  • Density: 1.36 g/cm3
  • Refractive index: 1.579
  • Safety Statements: R40
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 218-370-9
  • Molecular Weight: 410.451526
  • InchiKey: WXURHACBFYSXBI-GQKYHHCASA-N
  • InChI: InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,
    24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,
    6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1
  • Risk Statements: S22;S36
  • Molecular Formula: C22H28F2O5
  • Molecular Structure:CAS No:2135-17-3 (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,<br />17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,<br />16-octahydrocyclopenta[a]phenanthren-3-one

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  • China Hubei Gedian Humanwell Pharmaceutical Co., Ltd. [Manufacturers]
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2135-17-3 Flumethasone

  • Flumethasone Kind API Species Corticosteroid CAS 2135-17-3 Formula C22H28F2O5 We produce: Desonide 638-94-8 Flumethasone 2135-17-3 Diflucortolone valerate 59198-70-8 Deflazacort 14484-47-0 Desoximetasone 382-67-2 Difluprednate 23674-86-4 Fludrocortis...
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2135-17-3 FLUMETHASONE

  • China Taifa Pharma [Manufacturer]
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References of (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
16-octahydrocyclopenta[a]phenanthren-3-one
Title: Flumethasone
CAS Registry Number: 2135-17-3
CAS Name: (6a,11b,16a)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
Synonyms: 6a,9a-difluoro-16a-methylprednisolone; 6a-fluorodexamethasone
Trademarks: Aniprime (Syntex Diamond); Cortexilar (Veterinaria); Flucort (Syntex); Methagon (Corvel)
Molecular Formula: C22H28F2O5
Molecular Weight: 410.45
Percent Composition: C 64.38%, H 6.88%, F 9.26%, O 19.49%
Literature References: Prepn: GB 902292; F. H. Lincoln et al., US 3499016 (1962, 1970 both to Upjohn). Prepn of the 21-acetate: J. A. Edwards et al., J. Am. Chem. Soc. 81, 3156 (1959); 82, 2318 (1960).
 
Derivative Type: 21-Acetate
Molecular Formula: C24H30F2O6
Molecular Weight: 452.49
Percent Composition: C 63.70%, H 6.68%, F 8.40%, O 21.22%
Properties: Crystals from acetone + hexane, mp 260-264°. [a]D +91°. uv max (ethanol): 237 nm (log e 4.16).
Melting point: mp 260-264°
Optical Rotation: [a]D +91°
Absorption maximum: uv max (ethanol): 237 nm (log e 4.16)
 
Derivative Type: 21-Pivalate
CAS Registry Number: 2002-29-1
Trademarks: Locacorten (Novartis); Locorten (Novartis); Lorinden (Polfa)
Molecular Formula: C27H36F2O6
Molecular Weight: 494.57
Percent Composition: C 65.57%, H 7.34%, F 7.68%, O 19.41%
 
Therap-Cat: Glucocorticoid; anti-inflammatory.
Therap-Cat-Vet: Glucocorticoid.
Keywords: Glucocorticoid.