Home > Name List By d > Dexetimide.HCl China

CAS No 21888-98-2 , Dexetimide.HCl Search by region : China

  • Name: Dexetimide.HCl
  • Synonyms: [3,4'-Bipiperidine]-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, (S)-;Dexbenzetimide;BENZETIMIDE;DEXETIMIDE HCL;(+)-DEXETIMIDE HYDROCHLORIDE;3-PHENYL-1'-(PHENYLMETHYL)-[3,4'-BIPIPERIDINE]-2,6-DIONE HYDROCHLORIDE;(+)-(S)-3-Phenyl-1'-(phenylmethyl)-[3,4'-bipiperidine]-2,6-dione.HCl;Dextrobenzetimide;R 16470;Diapamide;Benzetimide;Dexetimide;Dexetimide.HCl;
  • CAS Registry Number:
  • Transport: 3249
  • Flash Point: 282.7°C
  • Boiling Point: 543.9°C at 760 mmHg
  • Density: 1.178g/cm3
  • Refractive index: 1.597
  • Safety Statements: RIDADR 3249HazardClass 6.1(b)PackingGroup III
  • Flash Point: 282.7°C
  • Molecular Weight: 362.46
  • InChI: InChI=1S/C23H26N2O2/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18/h1-10,20H,11-17H2,(H,24,26,27)
  • Molecular Formula: C23H26N2O2
  • Molecular Structure:CAS No:21888-98-2 Dexetimide.HCl

Related products

Select to

21888-98-2 Benzetimide

  • Benzetimide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

21888-98-2 Dexbenzetimide

  • Dexbenzetimide, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

21888-98-2 DEXETIMIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of Dexetimide.HCl
Title: Dexetimide
CAS Registry Number: 21888-98-2
CAS Name: (3S)-3-Phenyl-1￠-(phenylmethyl)-[3,4￠-bipiperidine]-2,6-dione
Synonyms: (S)-(+)-2-(1-benzyl-4-piperidyl)-2-phenylglutarimide; (+)-3-(1-benzyl-4-piperidyl)-3-phenylpiperidine-2,6-dione; (+)-1-benzyl-4-(2,6-dioxo-3-phenyl-3-piperidyl)piperidine; dextrobenzetimide; dexbenzetimide
Molecular Formula: C23H26N2O2
Molecular Weight: 362.46
Percent Composition: C 76.21%, H 7.23%, N 7.73%, O 8.83%
Literature References: The dextroenantiomer responsible for the pharmacological activity of racemic benzetimide, q.v. Resolution of isomers and comparative pharmacology: Janssen et al., Arzneim.-Forsch. 21, 1365 (1971). Abs config studies: van Wijngaarden et al., Life Sci. 9, part 1, 1289 (1970); Spek et al., Nature 232, 575 (1971). Clinical trials: De Smedt et al., J. Clin. Pharmacol. 10, 207 (1970).
Properties: Crystals, mp 181-183°. [a]D20 +125° (chloroform).
Melting point: mp 181-183°
Optical Rotation: [a]D20 +125° (chloroform)
 
Derivative Type: Hydrochloride
CAS Registry Number: 21888-96-0
Manufacturers' Codes: R-16470
Trademarks: Tremblex (Janssen)
Molecular Formula: C23H26N2O2.HCl
Molecular Weight: 398.93
Percent Composition: C 69.25%, H 6.82%, N 7.02%, O 8.02%, Cl 8.89%
Properties: Crystals, mp 270-275°. [a]D20 +125° (methanol). LD50 i.v. in rats: 45 mg/kg (Janssen).
Melting point: mp 270-275°
Optical Rotation: [a]D20 +125° (methanol)
Toxicity data: LD50 i.v. in rats: 45 mg/kg (Janssen)
 
Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian; Antimuscarinic.