CAS No 22916-47-8 , 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole Search by region : India

Name: 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
Synonyms: Minostate; Dactarin; Miconazolum; Vusion; Miconazolo; Monistat IV; Monistat-Derm; Daktarin IV;Monistat;1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole;
CAS Registry Number:22916-47-8
Transport: 3249
Melting Point: 159-163C
Flash Point: 289.5°C
Boiling Point: 555.1°Cat760mmHg
Density: 1.4g/cm³
Refractive index: 1.639
Safety Statements: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl− and NOx.
Hazard Symbols: Xn
Flash Point: 289.5°C
EINECS: 245-324-5
Molecular Weight: 416.12856
InchiKey: BYBLEWFAAKGYCD-UHFFFAOYSA-N
InChI: InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-
24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2
Risk Statements: 22
Molecular Formula: C₁₈H₁₄Cl₄N₂O
Molecular Structure:

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22916-47-8 MICONAZOLE

VARDA Biotech (P) Ltd. [Manufacturer]
Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
Fax: +91-22-6693 5687
Address: 110 & 111, Kartik Complex
New link Road, Andheri-(W)
Mumbai-400053, INDIA. null,nullIndia

22916-47-8 Miconazole

Ibis Chemie International [Manufacturers]
Tel: +91-22-22001993
Fax: +91-22-22088450
Address: 211 Dalamal Chambers,New Marine Lines,Mumbai 400020.India Mumbai,nullIndia

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References of 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

Title: Miconazole
CAS Registry Number: 22916-47-8
CAS Name: 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
Synonyms: 1-[2,4-dichloro-b-[(2,4-dichlorobenzyl)oxy]phenethyl]imidazole
Molecular Formula: C18H14Cl4N2O
Molecular Weight: 416.13
Percent Composition: C 51.95%, H 3.39%, Cl 34.08%, N 6.73%, O 3.84%
Literature References: Prepn: E. F. Godefroi et al., J. Med. Chem. 12, 784 (1969); E. F. Godefroi, J. Heeres, DE 1940388; eidem, US 3717655 (1970, 1973 to Janssen). Clinical evaluation: Brugmans et al., Arch. Dermatol. 102, 428 (1970); Godts et al., Arzneim.-Forsch. 21, 256 (1971). Review: P. Janssen, W. Van Bever, in Pharmacological and Biochemical Properties of Drug Substances vol. 2, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1979) pp 333-354; R. C. Heel et al., Drugs 19, 7-30 (1980).

Derivative Type: Nitrate
CAS Registry Number: 22832-87-7
Manufacturers' Codes: R-14889
Trademarks: Aflorix (Gramon); Albistat (Ortho); Andergin (ISOM); Brentan (Janssen); Conoderm (C-Vet); Conofite (Mallinckrodt); Daktar (Janssen); Daktarin (Janssen); Deralbine (Andromaco); Dermonistat (Ortho); Epi-Monistat (Cilag); Florid (Mochida); Fungiderm (Janssen); Fungisdin (Isdin); Gyno-Daktarin (Janssen); Gyno-Monistat (Cilag-Chemie); Micatin (J & J); Miconal Ecobi (Ecobi); Micotef (LPB); Monistat (Cilag-Chemie); Prilagin (Gambar); Vodol (Andromaco)
Molecular Formula: C18H14Cl4N2O.HNO3
Molecular Weight: 479.14
Percent Composition: C 45.12%, H 3.16%, Cl 29.60%, N 8.77%, O 13.36%
Properties: Crystals, mp 170.5° (Godefroi, Heeres, 1970); 184-185° (Godefroi).
Melting point: mp 170.5° (Godefroi, Heeres, 1970); 184-185° (Godefroi)

Derivative Type: (+)-Form nitrate
Properties: mp 135.3°. [a]D20 +59° (methanol).
Melting point: mp 135.3°
Optical Rotation: [a]D20 +59° (methanol)

Derivative Type: (-)-Form nitrate
Properties: mp 135°. [a]D20 -58° (methanol).
Melting point: mp 135°
Optical Rotation: [a]D20 -58° (methanol)

Therap-Cat: Antifungal (topical).
Therap-Cat-Vet: Antifungal (topical).
Keywords: Antifungal (Synthetic); Imidazoles.