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CAS No 23593-75-1 , 1-[(2-chlorophenyl)-diphenylmethyl]imidazole Search by region : Germany

  • Name: 1-[(2-chlorophenyl)-diphenylmethyl]imidazole
  • Synonyms: Empecid;Lotrimin; Gyne-Lotrimin; Clotrimazol; Mycelex;1-[(2-chlorophenyl)-diphenylmethyl]imidazole; Mykosporin; Canesten; Gyne lotrimin; Mycosporin;
  • CAS Registry Number:
  • Melting Point: 147-149 ºC
  • Flash Point: 245.5°C
  • Boiling Point: 482.3°Cat760mmHg
  • Density: 1.13g/cm3
  • Refractive index: 1.616
  • Safety Statements: 26-36
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 245.5°C
  • EINECS: 245-764-8
  • Molecular Weight: 344.83678
  • InchiKey: VNFPBHJOKIVQEB-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,
    18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
  • Risk Statements: 22-36/38
  • Molecular Formula: C22H17ClN2
  • Molecular Structure:CAS No:23593-75-1 1-[(2-chlorophenyl)-diphenylmethyl]imidazole

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23593-75-1 CLOTRIMAZOLE

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany null,nullGermany
Contact Supplier

23593-75-1 CLOTRIMAZOLE

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
Contact Supplier

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References of 1-[(2-chlorophenyl)-diphenylmethyl]imidazole
Title: Clotrimazole
CAS Registry Number: 23593-75-1
CAS Name: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole
Synonyms: 1-(o-chloro-a,a-diphenylbenzyl)imidazole; 1-[a-(2-chlorophenyl)benzhydryl]imidazole; 1-[(o-chlorophenyl)diphenylmethyl]imidazole; diphenyl-(2-chlorophenyl)-1-imidazolylmethane; 1-(o-chlorotrityl)imidazole
Manufacturers' Codes: FB-5097; Bay b 5097
Trademarks: Canesten (Bayer); Canifug (Wolff); Empecid (Bayer-Takeda); Gyne-Lotrimin (Schering-Plough); Lotrimin (Schering-Plough); Mono-Baycuten; Mycelex-G (Miles); Mycofug (Hermal); Mycosporin (Bayer); Pedisafe (Sagitta); Rimazole (Cheil Sugar); Tibatin (Dak); Trimysten
Molecular Formula: C22H17ClN2
Molecular Weight: 344.84
Percent Composition: C 76.63%, H 4.97%, Cl 10.28%, N 8.12%
Literature References: Prepn: K. H. Buechel et al., ZA 6805392; eidem, US 3705172 (1969, 1972 both to Bayer). Pharmacology: Plempel et al., Antimicrob. Agents Chemother. 1969, 271; eidem, Dtsch. Med. Wochenschr. 94, 1356 (1969). Clinical findings: Oberste-Lehn et al., ibid. 1365. Series of articles on prepn, toxicology, pharmacokinetics, clinical studies: Arzneim.-Forsch. 22, 1260-1272, 1276-1299 (1972). Toxicity: D. Tettenborn, ibid. 1276. Comprehensive description: J. G. Hoogerheide, B. E. Wyka, Anal. Profiles Drug Subs. 11, 225-255 (1982).
Properties: Crystals, mp 147-149°. A weak base, slightly sol in water, benzene, toluene; sol in acetone, chloroform, ethyl acetate, DMF. Hydrolyzes rapidly upon heating in aq acids. LD50 in male mice, rats (mg/kg): 923, 708 orally (Tettenborn).
Melting point: mp 147-149°
Toxicity data: LD50 in male mice, rats (mg/kg): 923, 708 orally (Tettenborn)
 
Derivative Type: Hydrochloride
Molecular Formula: C22H17ClN2.HCl
Molecular Weight: 381.30
Percent Composition: C 69.30%, H 4.76%, Cl 18.60%, N 7.35%
Properties: mp 159°.
Melting point: mp 159°
 
Therap-Cat: Antifungal.
Therap-Cat-Vet: Antifungal.
Keywords: Antifungal (Synthetic); Imidazoles.