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CAS No 23602-78-0 , benfluorex Search by region : China

  • Name: benfluorex
  • Synonyms: Ethanol, 2-(alpha-methyl-m-trifluoromethylphenethylamino)-, benzoate; 2-(alpha-methyl-m-trifluoromethylphenethylamino)ethanolbenzoate;benfluorex; benfluramate; Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, benzoate; 2-((1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl)amino)ethyl benzoate; 2-[[alpha-Methyl-m-(trifluoromethyl)phenethyl]amino]ethanol benzoate (ester); 2-(alpha-Methyl-m-trifluoromethylphenethylamino)ethanol benzoate;Benfluorex Hydrochloride; 2-(alpha-methyl-m-trifluoromethylphenethylamino)-ethanobenzoate;
  • CAS Registry Number:
  • Density: 1.183g/cm3
  • Refractive index: 1.515
  • EINECS: 245-777-9
  • Molecular Weight: 369.38
  • InChI: InChI=1/C19H20F3NO2/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16/h2-9,13-14,23H,10-12H2,1H3
  • Molecular Formula: C19H22F3NO3
  • Molecular Structure:CAS No:23602-78-0 benfluorex

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References of benfluorex
Title: Benfluorex
CAS Registry Number: 23602-78-0
CAS Name: 2-[[1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol benzoate (ester)
Synonyms: 2-[[a-methyl-m-(trifluoromethyl)phenethyl]amino]ethanol benzoate (ester); 1-(m-trifluoromethylphenyl)-2-(b-benzoyloxyethyl)aminopropane; N-(2-benzoyloxyethyl)norfenfluramine; benfluramate
Manufacturers' Codes: S-780; SE-780
Molecular Formula: C19H20F3NO2
Molecular Weight: 351.36
Percent Composition: C 64.95%, H 5.74%, F 16.22%, N 3.99%, O 9.11%
Literature References: Prepn from 1-(m-trifluoromethyl)-2-(b-hydroxyethyl)aminopropane and benzoyl chloride: L. Beregi et al., FR 1517587; eidem, US 3607909 (1968, 1971 both to Sci. Union et Cie, Soc. Franc. Rech. Med.). Metabolism studies: A. H. Beckett et al., J. Pharm. Pharmacol. 23, 950 (1971); 24, 281 (1972). Pharmacology: D. N. Brindley et al., ibid. 28, 670 (1976); P. Pritchard et al., ibid. 29, 343 (1977); eidem, Biochem. J. 166, 639 (1977).
Properties: Colorless oil.
 
Derivative Type: Hydrochloride
CAS Registry Number: 23642-66-2
Manufacturers' Codes: S-992; JP-992
Trademarks: Minolip (Master); Mediator (Biopharma); Mediaxal (Servier)
Molecular Formula: C19H20F3NO2.HCl
Molecular Weight: 387.82
Percent Composition: C 58.84%, H 5.46%, F 14.70%, N 3.61%, O 8.25%, Cl 9.14%
Properties: Crystals from ethyl acetate, mp 161-162°.
Melting point: mp 161-162°
 
Therap-Cat: Antilipemic.
Keywords: Antilipemic.