Home > Name List By 1 > 10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1, 4]benzodiazepin-6-one

CAS No 24166-13-0 , 10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,
4]benzodiazepin-6-one

  • Name: 10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,
    4]benzodiazepin-6-one
  • Synonyms: Cloxazolamum [INN-Latin]; CS 370; Enadel;Olcadil; MT 14-411; Cloxazolazepam; 24166-13-0; Cloxazolam [INN:JAN]; Sepazon;10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,
    4]benzodiazepin-6-one;
  • CAS Registry Number:
  • Transport: 3249
  • Density: 1.49 g/cm3
  • Refractive index: 1.692
  • Safety Statements: Moderately toxic by ingestion. An experimental teratogen. When heated to decomposition it emits toxic fumes of Cl and NOx. A minor tranquilizer. See also DIAZEPAM.
  • Molecular Weight: 349.21126
  • InchiKey: ZIXNZOBDFKSQTC-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H14Cl2N2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21
    (7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22)
  • Molecular Formula: C17H14Cl2N2O2
  • Molecular Structure:CAS No:24166-13-0 10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,<br />4]benzodiazepin-6-one
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24166-13-0 Cloxazolam

  • Cloxazolam, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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24166-13-0 Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one,10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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24166-13-0 Cloxazolam

  • Cloxazolam, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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24166-13-0 Cloxazolam

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24166-13-0 Cloxazolam

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24166-13-0 CLOXAZOLAM

  • China HANGZHOU ONICON CHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-571-85054016/ +86-571-85104679
  • Fax: +86-571-85054082
  • Address: HANGZHOU ONICON CHEMICAL CO.,LTD
    303-306 Hangzhou yiyao Building,
    No.439 Zhongshan North Rd.
    Hangzhou China
    Phone : +86-571-85054016
    Fax: +86-571-85054082
    E-Mail1: cjw9999@163.com ,China
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24166-13-0 Cloxazolam

  • Cloxazolam
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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24166-13-0 CLOXAZOLAM

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of 10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,
4]benzodiazepin-6-one
Title: Cloxazolam
CAS Registry Number: 24166-13-0
CAS Name: 10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
Synonyms: 7-chloro-5-(2-chlorophenyl)tetrahydrooxazolo[5,4-b]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-one; 10-chloro-11b-(2-chlorophenyl)-2,3,5,6,7,11b-hexahydrobenzo[6,7]-1,4-diazepino[5,4-b]oxazol-6-one; 10-chloro-11b-(2-chlorophenyl)-6-oxo-2,3,5,6,7,11b-hexahydrooxazolo[3,2-d][1,4]benzodiazepine
Manufacturers' Codes: CS-370
Trademarks: Betavel (Sanofi Winthrop); Enadel (Pfizer); Lubalix (Lubapharm); Olcadil (Sandoz); Sepazon (Sankyo); Tolestan (Roemmers)
Molecular Formula: C17H14Cl2N2O2
Molecular Weight: 349.21
Percent Composition: C 58.47%, H 4.04%, Cl 20.30%, N 8.02%, O 9.16%
Literature References: Prepn: R. Tachikawa et al., DE 1812252 and DE 1952201; eidem, US 3772371 and US 3696094 (1969, 1970, 1973, 1972 all to Sankyo); T. Miyadera et al., J. Med. Chem. 14, 520 (1971). Pharmacology: T. Kamioka et al., Arzneim.-Forsch. 22, 884 (1972). Metabolism: Murata et al., Chem. Pharm. Bull. 21, 404 (1973). Multicenter trials and complementary studies: K. A. Fischer-Cornelssen, Arzneim.-Forsch. 31, 1757 (1981).
Properties: Crystals, mp 202-204° (dec). Freely sol in glacial acetic acid; sparingly sol in chloroform; slightly sol in acetone, dehydrated ethanol, ethyl acetate, benzene. Practically insol in water. LD50 in mice (g/kg): 3.3 orally; >2.0 i.p. (Kamioka).
Melting point: mp 202-204° (dec)
Toxicity data: LD50 in mice (g/kg): 3.3 orally; >2.0 i.p. (Kamioka)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.14.
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic; Benzodiazepine Derivatives.