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CAS No 2438-72-4 , 2-(4-butoxyphenyl)-N-hydroxyacetamide

  • Name: 2-(4-butoxyphenyl)-N-hydroxyacetamide
  • Synonyms: 2-(4-butoxyphenyl)-N-hydroxyacetamide; Droxaryl;Parfenac; 2438-72-4; Bufexamic acid; Anderm; Bufexamaco; Feximac; Bufexamacum; Malipuran;
  • CAS Registry Number:
  • Melting Point: 161 - 162
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.12g/cm3
  • Refractive index: 1.53
  • Safety Statements: Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: °C
  • EINECS: 219-451-1
  • Molecular Weight: 223.26828
  • InchiKey: MXJWRABVEGLYDG-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,
    2-3,8-9H2,1H3,(H,13,14)
  • Molecular Formula: C12H17NO3
  • Molecular Structure:CAS No:2438-72-4 2-(4-butoxyphenyl)-N-hydroxyacetamide

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References of 2-(4-butoxyphenyl)-N-hydroxyacetamide
Title: Bufexamac
CAS Registry Number: 2438-72-4
CAS Name: 4-Butoxy-N-hydroxybenzeneacetamide
Synonyms: 2-(p-butoxyphenyl)acetohydroxamic acid; 2-[p-(butyloxy)phenyl]acetohydroxamic acid
Manufacturers' Codes: CP-1044-J3
Trademarks: Droxarol (Pharmos); Droxaryl (Continental Pharma); Feximac (Nicholas); Malipuran (Heumann); Mofenar (C.E.P.A.); Norfemac (HMR); Parfenac (Lederle); Parfenal (Cyanamid)
Molecular Formula: C12H17NO3
Molecular Weight: 223.27
Percent Composition: C 64.55%, H 7.67%, N 6.27%, O 21.50%
Literature References: Synthesis: N. P. Buu-Ho? et al., Compt. Rend. 261, 2259 (1965); eidem, BE 661226; eidem, US 3479396 (1965, 1969 to Madan). Pharmacology and toxicology: Lambelin et al., Med. Pharmacol. Exp. 15, 545 (1966).
Properties: Needles from acetone, mp 153-155°. Practically insol in water. LD50 orally in mice, rats: >8, >4 g/kg (Lambelin).
Melting point: mp 153-155°
Toxicity data: LD50 orally in mice, rats: >8, >4 g/kg (Lambelin)
Therap-Cat: Anti-inflammatory, analgesic, antipyretic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives; Antipyretic.