Home > Name List By 1 > 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole

CAS No 27523-40-6 , 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole

  • Name: 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole
  • Synonyms: Travogen; Fazol; 27523-40-6; EINECS 248-508-3; Isoconazol [INN-Spanish]; Isoconazolum [INN-Latin];1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole;Isoconazol; Isoconazolum;
  • CAS Registry Number:
  • Flash Point: 289.5°C
  • Boiling Point: 555.1°Cat760mmHg
  • Density: 1.4g/cm3
  • Refractive index: 1.625
  • Flash Point: 289.5°C
  • EINECS: 248-508-3
  • Molecular Weight: 416.12856
  • InchiKey: MPIPASJGOJYODL-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H14Cl4N2O/c19-12-4-5-13(17(22)8-12)18(9-24-7-6-23-11-24)25-
    10-14-15(20)2-1-3-16(14)21/h1-8,11,18H,9-10H2
  • Molecular Formula: C18H14Cl4N2O
  • Molecular Structure:CAS No:27523-40-6 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole

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27523-40-6 ISOCONAZOLE

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27523-40-6 ISOCONAZOLE

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References of 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole
Title: Isoconazole
CAS Registry Number: 27523-40-6
CAS Name: 1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole
Synonyms: 1-[2,4-dichloro-b-[(2,6-dichlorobenzyl)oxy]phenethyl]imidazole
Molecular Formula: C18H14Cl4N2O
Molecular Weight: 416.13
Percent Composition: C 51.95%, H 3.39%, Cl 34.08%, N 6.73%, O 3.84%
Literature References: Prepn: E. F. Godefroi et al., J. Med. Chem. 12, 784 (1969); eidem, DE 1940388; eidem, US 3717655 and US 3839574 (1970, 1973, 1974 all to Janssen). In vitro activity: H. J. Kessler, Arzneim.-Forsch. 29, 1344 (1979). Animal study: H. J. Kessler et al., ibid. 1352. Antimicrobial activity in humans: H. Wendt, H. J. Kessler, ibid. 846. Bioavailability: U. T?uber, M. Rzadkiewicz, Mykosen 22, 201 (1979).
 
Derivative Type: Nitrate
CAS Registry Number: 24168-96-5
Manufacturers' Codes: R-15454
Trademarks: Fazol (Schering); Gyno-Travogen (Schering AG); Travogen (Schering AG); Travogyn (Keymer)
Molecular Formula: C18H14Cl4N2O.HNO3
Molecular Weight: 479.14
Percent Composition: C 45.12%, H 3.16%, Cl 29.60%, N 8.77%, O 13.36%
Properties: Solid, mp 182-183°.
Melting point: mp 182-183°
 
Therap-Cat: Antibacterial; antifungal.
Keywords: Antifungal (Synthetic); Imidazoles.