Home > Name List By 1 > 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine

CAS No 28289-54-5 , 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine

  • Name: 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine
  • Synonyms: CHEBI:17963;MPTP;1-methyl-4-phenyl-3,6-dihydro-2H-pyridine; CCRIS 2186; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; HSDB 6942; 28289-54-5;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 2
  • Flash Point: 105.8°C
  • Boiling Point: 128-132 °C12 mm Hg(lit.)
  • Density: 1.001g/cm3
  • Refractive index: 1.553
  • Safety Statements: A poison by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx.
  • Hazard Symbols: A poison. A reproductive hazard.
  • Flash Point: 105.8°C
  • EINECS: 248-939-7
  • Molecular Weight: 173.2542
  • InchiKey: PLRACCBDVIHHLZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H15N/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h2-7H,8-10H2,1H3
  • Risk Statements: 25-39/23/24/25
  • Molecular Formula: C12H15N
  • Molecular Structure:CAS No:28289-54-5 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine

Related products

Search by region :

Select to

28289-54-5 Pyridine,1,2,3,6-tetrahydro-1-methyl-4-phenyl-

Contact Supplier

28289-54-5 1-Methyl-4-phenyl-1,2,3,6-tetrahydroxpyridine

  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydroxpyridine 1-Methyl-4-phenyl-piperidine-3-en 1-Methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine hydrochloride MPTP hydrochloride 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Mptp
  • Netherlands Vitas-M Laboratory [Manufacturer]
  • Tel: +31 (0)55 50 500 33
  • Fax: +31 (0)55 50 500 34
  • Address: PO Box 200477302 HA ApeldoornNETHERLANDS 7302 HA Apeldoorn,nullNetherlands
Contact Supplier

28289-54-5 1-Methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine hydrochloride

  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine hydrochlorideMPTP hydrochloride, 99%
  • Netherlands Axon Medchem BV [Manufacturer]
  • Tel: +31-50-3118007
  • Fax: +31-50-3600390
  • Address: Biotech Center UMCG Postbus 770 9700AT GroningenNETHERLANDS Groningen,nullNetherlands
Contact Supplier

28289-54-5 1-Methyl-4-phenyl-1,2,3,6-tetrahydroxpyridine

  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydroxpyridine
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

28289-54-5 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROXPYRIDINE

  • 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROXPYRIDINE
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

Select to

1/1
References of 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine
Title: MPTP
CAS Registry Number: 28289-54-5
CAS Name: 1,2,3,6-Tetrahydro-1-methyl-4-phenylpyridine
Synonyms: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Molecular Formula: C12H15N
Molecular Weight: 173.25
Percent Composition: C 83.19%, H 8.73%, N 8.08%
Literature References: Piperidine derivative which causes irreversible symptoms of parkinsonism in humans, monkeys. Prepn as hydrochloride by Grignard reaction: A. Ziering et al., J. Org. Chem. 12, 894 (1947). Alternative prepn: C. J. Schmidle, R. C. Mansfield, J. Am. Chem. Soc. 78, 425 (1956). Identification as impurity in "synthetic heroin" and effect on drug users: J. W. Langston et al., Science 219, 979 (1983). Selective destruction of dopaminergic neurons in primates: R. S. Burns et al., Proc. Natl. Acad. Sci. USA 80, 4546 (1983). In vitro metabolism by rat brain monoamine oxidase to 1-methyl-4-phenylpyridinium ion (MPP+): K. Chiba et al., Biochem. Biophys. Res. Commun. 120, 574 (1984). Studies on mechanism of neurotoxicity: J. W. Langston et al., Science 225, 1480 (1984); S. P. Markey et al., Nature 311, 464 (1984). Binding studies in rat brain: C. M. Wieczorek et al., Eur. J. Pharmacol. 98, 453 (1984); B. Parsons, T. C. Rainbow, ibid. 102, 375 (1984); in rat, human brain: J. A. Javitch et al., Proc. Natl. Acad. Sci. USA 81, 4591 (1984). Comparison of idiopathic and MPTP-induced parkinsonism in humans: R. S. Burns et al., N. Engl. J. Med. 312, 1418 (1985). Review: T. P. Singer et al., Trends Biochem. Sci. 12, 266-270 (1987); L. M. Sayre, Toxicol. Lett. 48, 121-149 (1989).
Properties: Crystals from heptane, mp 40-42°. bp0.8 85-90°.
Melting point: mp 40-42°
Boiling point: bp0.8 85-90°