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CAS No 28721-07-5 , 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide

  • Name: 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
  • Synonyms: Oxcarbazepime; Oxcarbamazepine; Oxcarbazepinum; Epilexter; Timox;Trileptal; Oxcarbazepina;5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide; 28721-07-5; Oxacarbazepine;
  • CAS Registry Number:
  • Transport: 20kgs
  • Flash Point: 230
  • Boiling Point: 457
  • Density: 1.329g/cm3
  • Refractive index: 1.661
  • Hazard Symbols: UN NO.
  • Flash Point: 230
  • EINECS: 249-188-8
  • Molecular Weight: 252.26798
  • InchiKey: CTRLABGOLIVAIY-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13
    (11)17/h1-8H,9H2,(H2,16,19)
  • Molecular Formula: C15H12N2O2
  • Molecular Structure:CAS No:28721-07-5 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide

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References of 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
Title: Oxcarbazepine
CAS Registry Number: 28721-07-5
CAS Name: 10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide
Synonyms: oxacarbazepine
Manufacturers' Codes: GP-47680
Trademarks: Trileptal (Novartis)
Molecular Formula: C15H12N2O2
Molecular Weight: 252.27
Percent Composition: C 71.42%, H 4.79%, N 11.10%, O 12.68%
Literature References: Ketoderivative of carbamazepine, q.v. Prepn: W. Schindler, DE 2011087 (1970 to Geigy); idem, US 3642775 (1972 to Ciba-Geigy). Improved prepn: D. Kaufmann et al., Tetrahedron Lett. 45, 5275 (2004). Metabolism: H. Schütz et al., Xenobiotica 16, 769 (1986). Hyponatremic effects: O. A. Nielsen et al., Epilepsy Res. 2, 269 (1988). Determn of oxcarbazepine and main metabolites by GC in plasma: G. E. Von Unruh, W. D. Paar, J. Chromatogr. 345, 67 (1985); by HPLC: A. A. Elyas, V. D. Goldberg, ibid. 528, 473 (1990). Clinical evaluation in treatment of epilepsy: M. Dam et al., Epilepsy Res. 3, 70 (1989); in management of trigeminal neuralgia: J. M. Zakrzewska, P. N. Patsalos, J. Neurol. Neurosurg. Psychiatry 52, 472 (1989). Review of pharmacology and therapeutic efficacy: A. Beydoun, E. Kutluay, Expert Opin. Pharmacother. 3, 59-71 (2001).
Properties: Crystals from ethanol, mp 215-216°.
Melting point: mp 215-216°
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant.