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CAS No 298-46-4 , benzo[b][1]benzazepine-11-carboxamide

  • Name: benzo[b][1]benzazepine-11-carboxamide
  • Synonyms: Tegretal; Carbatrol; Epitol; Finlepsin;Tegretol; Carbazepine; Carbamezepine; Neurotol;benzo[b][1]benzazepine-11-carboxamide; Carbamazepen;
  • CAS Registry Number:
  • Transport: 20kgs
  • Melting Point: 189-192 ºC
  • Flash Point: 202.4°C
  • Boiling Point: 411°Cat760mmHg
  • Density: 1.266g/cm3
  • Refractive index: 1.669
  • Safety Statements: R22;R42/43
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 202.4°C
  • EINECS: 206-062-7
  • Molecular Weight: 236.26858
  • InchiKey: FFGPTBGBLSHEPO-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)
    17/h1-10H,(H2,16,18)
  • Risk Statements: S22;S24;S37
  • Molecular Formula: C15H12N2O
  • Molecular Structure:CAS No:298-46-4 benzo[b][1]benzazepine-11-carboxamide

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References of benzo[b][1]benzazepine-11-carboxamide
Title: Carbamazepine
CAS Registry Number: 298-46-4
CAS Name: 5H-Dibenz[b,f]azepine-5-carboxamide
Synonyms: 5-carbamoyl-5H-dibenz[b,f]azepine
Manufacturers' Codes: G-32883
Trademarks: Biston (Slovakofarma); Calepsin (Orion); Carbatrol (Shire); Epitol (Teva); Finlepsin (AWD); Sirtal (Dura); Stazepine (Polfa); Tegretol (Novartis); Telesmin (Yoshitomi); Timonil (Desitin)
Molecular Formula: C15H12N2O
Molecular Weight: 236.27
Percent Composition: C 76.25%, H 5.12%, N 11.86%, O 6.77%
Literature References: Prepn: W. Schindler, US 2948718 (1960 to Geigy). Toxicity: E. G. Stenger, F. C. Roulet, Med. Exp. 11, 191 (1964). Review of GLC methods, pharmacokinetics and metabolism: S. Pynn?nen, Ther. Drug Monit. 1, 409-431 (1979). Comprehensive description: H. Y. Aboul-Enein, A. A. Al-Badr, Anal. Profiles Drug Subs. 9, 87-106 (1980). Review of clinical use in pediatric seizures: J. T. Gilman, DICP Ann. Pharmacother. 25, 1109-1112 (1991); in trigeminal neuralgia: A. Sidebottom, S. Maxwell, J. Clin. Pharm. Ther. 20, 31-35 (1995).
Properties: Crystals from abs ethanol + benzene, mp 190-193°. Sol in alcohol, acetone, propylene glycol. Practically insol in water. LD50 orally in mice, rats: 3750, 4025 mg/kg (Stenger, Roulet).
Melting point: mp 190-193°
Toxicity data: LD50 orally in mice, rats: 3750, 4025 mg/kg (Stenger, Roulet)
Therap-Cat: Anticonvulsant. In treatment of pain associated with trigeminal neuralgia.
Keywords: Anticonvulsant.