Home > Name List By 3 > 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N, N-dimethylpropan-1-amine

CAS No 303-53-7 , 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,
N-dimethylpropan-1-amine

  • Name: 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,
    N-dimethylpropan-1-amine
  • Synonyms: Ciclobenzaprina; Proeptatriene; Proheptatriene; Cyclobenzaprinum; Yurelax; Cyclobenz; Lisseril; Proheptatrien;Flexeril;3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,
    N-dimethylpropan-1-amine;
  • CAS Registry Number:
  • Density: 1.096 g/cm3
  • Water Solubility: Soluble in water
  • Safety Statements: Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 206-145-8
  • Molecular Weight: 275.38744
  • InchiKey: JURKNVYFZMSNLP-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H21N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-
    19(17)20/h3-6,8-14H,7,15H2,1-2H3
  • Molecular Formula: C20H21N
  • Molecular Structure:CAS No:303-53-7 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,<br />N-dimethylpropan-1-amine
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303-53-7 CYCLOBENZOPRINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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303-53-7 1-Propanamine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-

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303-53-7 Cyclobenzaprine

  • Cyclobenzaprine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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303-53-7 Cyclobenzaprine

  • Cyclobenzaprine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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303-53-7 Cyclobenzaprine

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
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303-53-7 Cyclobenzaprine

  • India Triveni Chemicals []
  • Tel: +91-(260)-2400022, 3258683
  • Fax: +91-(260)-2400022/3264008
  • Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195, ,India
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303-53-7 Cyclobenzaprine

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303-53-7 CYCLOBENZAPRINE-D3

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. ,India
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303-53-7 Cyclobenzaprine

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303-53-7 CYCLOBENZAPRINE-D3.HCL

  • United States EJY Tech, Inc. [Manufacturer]
  • Tel: 301-526-7059
  • Fax: 301-561-6521
  • Address: 9430 Key West Avenue
    Suite 220
    Rockville , MD 20850 ,United States
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References of 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,
N-dimethylpropan-1-amine
Title: Cyclobenzaprine
CAS Registry Number: 303-53-7
CAS Name: 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
Synonyms: N,N-dimethyl-5H-dibenzo[a,d]cyclohepten-D5,g-propylamine; 5-(3-dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene; 1-(3-dimethylaminopropylidene)-2,3:6,7-dibenzo-4-suberene; proheptatriene
Manufacturers' Codes: MK-130; Ro-4-1577; RP-9715
Molecular Formula: C20H21N
Molecular Weight: 275.39
Percent Composition: C 87.23%, H 7.69%, N 5.09%
Literature References: Prepn: GB 858187 (1961 to Hoffmann-La Roche); Villani et al., J. Med. Pharm. Chem. 5, 373 (1962); Winthrop et al., J. Org. Chem. 27, 230 (1962). Pharmacology: C. D. Barnes, W. L. Adams, Neuropharmacology 17, 445 (1978); N. N. Share, ibid. 721; and toxicology: J. Metysova et al., Arch. Int. Pharmacodyn. Ther. 144, 481 (1963). Metabolism: G. Belvedere et al., Biomed. Mass Spectrom. 1, 329 (1974); H. B. Hucker et al., Drug Metab. Dispos. 6, 184 (1978). Bioavailability: eidem, J. Clin. Pharmacol. 17, 719 (1977). Clinical studies: J. V. Basmajian, Arch. Phys. Med. Rehabil. 5, 58 (1978); B. R. Brown, J. Womble, J. Am. Med. Assoc. 240, 1151 (1978). Comprehensive description: M. L. Cotton, G. R. B. Down, Anal. Profiles Drug Subs. 17, 41-72 (1988).
Properties: bp1 175-180°. uv max: 224, 289 nm (log e 4.57, 4.02), (Villani et al.)
Boiling point: bp1 175-180°
Absorption maximum: uv max: 224, 289 nm (log e 4.57, 4.02), (Villani et al.)
 
Derivative Type: Hydrochloride
CAS Registry Number: 6202-23-9
Trademarks: Flexeril (Merck & Co.); Flexiban (Merck & Co.)
Molecular Formula: C20H21N.HCl
Molecular Weight: 311.85
Percent Composition: C 77.03%, H 7.11%, N 4.49%, Cl 11.37%
Literature References: Use as muscle relaxant: N. N. Share, FR 2100873 (1972 to Frosst), C.A. 78, 47801n (1973).
Properties: Crystals from isopropanol, mp 216-218°. Soly in water: >20 g/100 ml. Freely sol in water, methanol, ethanol; sparingly sol in isopropanol; slightly sol in chloroform, methylene chloride. Practically insol in hydrocarbons. uv max: 226, 295 nm (e 52300, 12000). LD50 in mice (mg/kg): 35 i.v., 250 orally (Metysova).
Melting point: mp 216-218°
Absorption maximum: uv max: 226, 295 nm (e 52300, 12000)
Toxicity data: LD50 in mice (mg/kg): 35 i.v., 250 orally (Metysova)
 
Therap-Cat: Muscle relaxant (skeletal).
Keywords: Muscle Relaxant (Skeletal).