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CAS No 31430-15-6 , methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate

  • Name: methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
  • Synonyms: Fluvermal; Flumoxane; Flubendazol;31430-15-6;methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate; Flubenol; Flubendazol [INN-Spanish]; Flutelmium; Flumoxal;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 290 ºC
  • Flash Point: °Cat760mmHg
  • Boiling Point: °Cat760mmHg
  • Density: 1.444 g/cm3
  • Refractive index: 1.685
  • Water Solubility: Insoluble
  • Hazard Symbols: UN NO.
  • Flash Point: °Cat760mmHg
  • EINECS: 250-624-4
  • Molecular Weight: 313.283183
  • InchiKey: CPEUVMUXAHMANV-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)
    9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)
  • Molecular Formula: C16H12FN3O3
  • Molecular Structure:CAS No:31430-15-6 methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate

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References of methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
Title: Flubendazole
CAS Registry Number: 31430-15-6
CAS Name: [5-(4-Fluorobenzoyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester
Synonyms: 5-(p-fluorobenzoyl)-2-benzimidazolecarbamic acid methyl ester
Manufacturers' Codes: R-17889
Trademarks: Flubenol (J & J); Flumoxal (Janssen); Fluvermal (Janssen)
Molecular Formula: C16H12FN3O3
Molecular Weight: 313.28
Percent Composition: C 61.34%, H 3.86%, F 6.06%, N 13.41%, O 15.32%
Literature References: Fluoro analog of mebendazole, q.v. Prepn: J. L. H. Van Gelder et al., DE 2029637; eidem, US 3657267 (1971, 1972 both to Janssen); A. H. M. Raeymaekers et al., Arzneim.-Forsch. 28, 586 (1978). Pharmacological, biological properties: D. Thienpont et al., ibid. 605. Anthelmintic activity in rats: O. Vanparijs et al., Vet. Parasitol. 5, 237 (1979); in pigs: E. Telléz-Giron et al., Am. J. Trop. Med. Hyg. 30, 135 (1981).
Properties: Crystals, mp 260°. LD50 in mice, rats, guinea pigs (mg/kg): >2560 orally (Thienpont).
Melting point: mp 260°
Toxicity data: LD50 in mice, rats, guinea pigs (mg/kg): >2560 orally (Thienpont)
Therap-Cat-Vet: Anthelmintic.