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CAS No 3397-23-7 , Ornipressin

  • Name: Ornipressin
  • Synonyms: 1-[19-Amino-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[4-amino-1-(carbamoylmethylcarbamoyl)butyl]pyrrolidine-2-carboxamide;8-Ornithinevasopressin;Ornipressin;-;
  • CAS Registry Number:
  • Density: 1.32 g/cm3
  • Refractive index: 1.582
  • EINECS: 222-253-8
  • Molecular Weight: 1042.19
  • InChI: InChI=1/C45H63N13O12S2/c46-16-4-8-28(39(64)51-21-37(50)62)53-44(69)34-9-5-17-58(34)45(70)33-23-72-71-22-27(47)38(63)54-30(19-25-10-12-26(59)13-11-25)42(67)55-31(18-24-6-2-1-3-7-24)41(66)52-29(14-15-35(48)60)40(65)56-32(20-36(49)61)43(68)57-33/h1-3,6-7,10-13,27-34,59H,4-5,8-9,14-23,46-47H2,(H2,48,60)(H2,49,61)(H2,50,62)(H,51,64)(H,52,66)(H,53,69)(H,54,63)(H,55,67)(H,56,65)(H,57,68)
  • Molecular Formula: C45H63N13O12S2
  • Molecular Structure:CAS No:3397-23-7 Ornipressin

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References of Ornipressin
Title: Ornipressin
CAS Registry Number: 3397-23-7
CAS Name: 8-L-Ornithinevasopressin
Synonyms: orn(8)-vasopressin
Manufacturers' Codes: POR-8
Molecular Formula: C45H63N13O12S2
Molecular Weight: 1042.19
Percent Composition: C 51.86%, H 6.09%, N 17.47%, O 18.42%, S 6.15%
Literature References: Synthetic analog of vasopressin, q.v., in which L-ornithine replaces L-arginine. Prepn: R. L. Huguenin, R. A. Boissonnas, Helv. Chim. Acta 46, 1669 (1963); eidem, FR 1396607 corresp to US 3299036 (1965, 1967 both to Sandoz). Separation by reversed-phase HPLC: K. Krummen, R. W. Frei, J. Chromatogr. 132, 27 (1977). Pharmacologic properties: B. Berde et al., Experientia 20, 42 (1964). Pharmacodynamics: S. Keppens, H. de Wulf, Biochim. Biophys. Acta 588, 63 (1979). Comparison of hemostatic and cardiovascular effects: L. Saarnivaara, P. Leander, Anaesthesist 26, 144 (1977). Clinical study: D. J. Adendorff, D. Davies, S. Afr. Med. J. 51, 131 (1977).
Therap-Cat: Vasoconstrictor.
Keywords: Antidiuretic.