CAS No 34368-04-2 , 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol Search by region : India

Name: 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
Synonyms: Dobutamina [INN-Spanish];racemic-Dobutamine; Inotrex;4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol; Dobutamina; Dobutrex; Dobutamine [USAN]; Dobutaminum [INN-Latin]; Dobutaminum;
CAS Registry Number:34368-04-2
Flash Point: 169.8°C
Boiling Point: 527.7°Cat760mmHg
Density: 1.189g/cm³
Safety Statements: 22-26-36/37/39
Hazard Symbols: Xn: Harmful;
Flash Point: 169.8°C
Molecular Weight: 301.38012
InchiKey: JRWZLRBJNMZMFE-UHFFFAOYSA-N
InChI: InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)
18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3
Risk Statements: 20/21/22-63
Molecular Formula: C₁₈H₂₃NO₃
Molecular Structure:

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           34368-04-2 Dobutamine
           IUPAC NAME-(RS)-4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol MOLECULAR FORMULA-C18H23NO3 MOLAR MASS-301.38 g/mol Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardiogenic shock. Dobutamine is use...
 
             Swapnroop Drugs and Pharmaceuticals
             
              [Manufacturer, Trading Company, Distributor/Wholesaler]
Tel: 91-240-6641875
Fax: 91-240-6641870
Address: Harsool aurangabad,maharashtraIndia

           34368-04-2 1,2-Benzenediol,4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-
           
             D.K. Pharma Chem Pvt. Ltd.
             
              [Manufacturers]
Tel: 91 -251 -2690111
Fax: 91 -251 -2690366
Address: F 32, M.I.D.C., Badlapur- 421503, Thane Dist, Maharashtra State, India. null,MaharashtraIndia

           34368-04-2 Dobutamine
           
             Sckomex Speciality Chemicals
             
              [Importer/Exporter]
Tel: +91-(251)-2490215
Address: A-102, Om-Sai sadan CHS Ltd, 1st Floor, Thakkurvaddi, Dombivli West, Maharashtra 421202,  Dombivli West,,MaharashtraIndia

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References of 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol

Title: Dobutamine
CAS Registry Number: 34368-04-2
CAS Name: 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol
Synonyms: (±)-4-[2-[[3-(p-hydroxyphenyl)-1-methylpropyl]amino]ethyl]pyrocatechol; 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-b-phenylethylamine
Manufacturers' Codes: Compound 81929
Molecular Formula: C18H23NO3
Molecular Weight: 301.38
Percent Composition: C 71.73%, H 7.69%, N 4.65%, O 15.93%
Literature References: b1-Adrenergic agonist; derivative of dopamine, q.v. Prepn: R. R. Tuttle, J. Mills, DE 2317710; eidem, US 3987200 (1973, 1976 to Lilly). Pharmacology: R. Weber, R. R. Tuttle in Pharmacological and Biochemical Properties of Drug Substances vol. 1, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1977) pp 109-124; E. H. Sonnenblick et al., N. Engl. J. Med. 300, 17 (1979). Comprehensive description: R. H. Bishara, H. B. Long, Anal. Profiles Drug Subs. 8, 139-158 (1979).

Derivative Type: Hydrochloride
CAS Registry Number: 49745-95-1
Trademarks: Inotrex (obsolete) (Lilly); Dobutrex (Lilly)
Molecular Formula: C18H23NO3.HCl
Molecular Weight: 337.84
Percent Composition: C 63.99%, H 7.16%, N 4.15%, O 14.21%, Cl 10.49%
Properties: Crystals, mp 184-186°. uv max (methanol): 281, 223 nm (e 4768, 14400). pKa 9.45. Rapidly oxidized at pH 11-13. LD50 i.v. in mice: ~73 mg/kg (Weber, Tuttle).
Melting point: mp 184-186°
pKa: pKa 9.45
Absorption maximum: uv max (methanol): 281, 223 nm (e 4768, 14400)
Toxicity data: LD50 i.v. in mice: ~73 mg/kg (Weber, Tuttle)

Therap-Cat: Cardiotonic.
Keywords: Cardiotonic.