Home > Name List By other > [(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7, 8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenant...

CAS No 35189-28-7 , [(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,
8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate

  • Name: [(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,
    8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate
  • Synonyms: Norgestimatum; Norgestimato;Dexnorgestrel acetime; Ortho Tri-Cyclen; Ortho-Prefest; Norgestimato [INN-Spanish]; Norgestimatum [INN-Latin];[(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,
    8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate;
  • CAS Registry Number:
  • Melting Point: 216 ºC
  • Flash Point: 254.9°C
  • Boiling Point: 497.9°Cat760mmHg
  • Density: 1.22g/cm3
  • Refractive index: 1.611
  • Flash Point: 254.9°C
  • Molecular Weight: 369.49714
  • InchiKey: KIQQMECNKUGGKA-NMYWJIRASA-N
  • InChI: InChI=1S/C23H31NO3/c1-4-22-12-10-19-18-9-7-17(24-26)14-16(18)6-8-20(19)
    21(22)11-13-23(22,5-2)27-15(3)25/h2,14,18-21,26H,4,6-13H2,1,
    3H3/b24-17+/t18-,19+,20+,21-,22-,23-/m0/s1
  • Molecular Formula: C23H31NO3
  • Molecular Structure:CAS No:35189-28-7 [(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,<br />8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate

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35189-28-7 NORGESTIMATE

  • United States Haorui Pharma-Chem Inc. [Manufacturer]
  • Tel: 732-906-7666
  • Fax: 732-906-1522
  • Address: Haorui Pharma-Chem Inc.
    100 menlo Park Drive
    Suite 316
    Edison, NJ 08837 null,nullUnited States
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35189-28-7 NORGESTIMATE

  • China CHINA CHEM SOURCE (HK) CO.,LTD. [Manufacturer]
  • Tel: +86-411-82808830
  • Fax: +86-411-82809230
  • Address: CHINA CHEM SOURCE (HK) CO.,LTD.
    RM.1628, Bank of East Asia Mansion
    7 Renmin Road, Zhongshan District,
    Dalian, China, 116001 null,nullChina
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35189-28-7 Norgestimate

  • China Sinosource Pharma Limited [Importer/Exporter]
  • Tel: +86-(20)-85581896, 33698005
  • Fax: +86-(20)-85581445
  • Address: 1-19L, Canada Garden, Tianhe, Guangzhou, Guangdong 510665, null,GuangdongChina
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35189-28-7 Norgestimate

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35189-28-7 Norgestimate

  • China Techwin Bio.& Pharm.Technology Limited [Manufacturers]
  • Tel: +86-755-8261 6423
  • Fax: +86-755-8261 9449
  • Address: 409 Zhongzhen Bldg., No.68 Luofang Road, Shenzhen,518003, Guangdong, China Shenzhen,GuangdongChina
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35189-28-7 NORGESTIMATE

  • China Beijing Zizhu Pharmaceutical Co.,Ltd [Manufacturer]
  • Tel: +86-10-62250847/ +86-10-62250847
  • Fax: +86-10-62250810
  • Address: Beijing Zizhu Pharmaceutical Co., LTD, International Trade Department
    No.44 Honglian Nancun, Haidian District, Beijing, 100082 null,nullChina
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  • China Zhejiang Horde Pharma Co., Ltd. [Manufacturers]
  • Tel: +86-(571)-85114466
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  • Address: Rm.608,Guangfu Building,No.161 Haier Lane, Zhejiang, Hangzhou,ZhejiangChina
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References of [(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,
8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate
Title: Norgestimate
CAS Registry Number: 35189-28-7
CAS Name: (17a)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime
Synonyms: (+)-13-ethyl-17-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one oxime acetate (ester); 17a-acetoxy-13-ethyl-17-ethynylgon-4-en-3-one oxime; dexnorgestrel acetime
Manufacturers' Codes: D-138; ORF-10131
Molecular Formula: C23H31NO3
Molecular Weight: 369.50
Percent Composition: C 74.76%, H 8.46%, N 3.79%, O 12.99%
Literature References: Acetate oxime of D-norgestrel, q.v. Prepn: A. P. Shroff, DE 2633210; idem, US 4027019 (both 1977 to Ortho). HPLC determn: P. A. Lane et al., J. Pharm. Sci. 76, 44 (1987). Pharmacology: D. W. Hahn et al., Contraception 16, 541 (1977); J. Killinger et al., ibid. 32, 311 (1985). Pharmacodynamics: H. S. Weintraub et al., J. Pharm. Sci. 67, 1406 (1978). Metabolism in female monkeys: S. F. Sisenwine et al., Contraception 15, 25 (1977); in women: K. B. Alton et al., ibid. 29, 19 (1984). Clinical trial as a contraceptive in combination with ethinyl estradiol: B. Rubio-Lotvin, R. Gonzales-Ansorena, Acta Eur. Fertil. 9, 1 (1978).
Properties: Crystals from methylene chloride, mp 214-218°. [a]D25 +110°.
Melting point: mp 214-218°
Optical Rotation: [a]D25 +110°
 
Derivative Type: Mixture with ethinyl estradiol
CAS Registry Number: 79871-54-8
Trademarks: Cilest (Cilag); Ortho Cyclen (Ortho); Ortho Tri-Cyclen (Ortho); Ortrel (Ortho); TriCilest (Cilag)
 
Therap-Cat: Progestogen. In combination with estrogen as oral contraceptive.
Keywords: Contraceptive (Oral); Progestogen.