Home > Name List By r > Ribavirin

CAS No 36791-04-5 , Ribavirin

  • Name: Ribavirin
  • Synonyms: Ribavirin; Tribavirin; rtca; vilona; tribavirin;Ribavirin; Vilona;Biopolymers; virazole;1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide; RTCA; Biopolymers; viramid; Virazole; virazid; Virazid; Viramid; 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide; ICN-1229;
  • CAS Registry Number:
  • Melting Point: 174-176 ºC
  • Flash Point: 340.7ºC
  • Boiling Point: 639.8 ºC at 760 mmHg
  • Density: 2.08 g/cm3
  • Refractive index: -36 ° (C=1, H2O)
  • Water Solubility: >=10 G/100 ML AT 19 ºC
  • Safety Statements: Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Used as an antiviral agent. When heated to decomposition it emits toxic fumes of NOx.Analytical Methods:   For occupational chemical analysis use NIOSH: Ribavirin 5027.
  • Hazard Symbols: Mildly toxic by ingestion. An experimental teratogen.
  • Flash Point: 340.7ºC
  • Molecular Weight: 244.21
  • InChI: InChI=1/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
  • Risk Statements: 61
  • Molecular Formula: C8H12N4O5
  • Molecular Structure:CAS No:36791-04-5 Ribavirin

Related products

Search by region :

Select to

36791-04-5 RIBAVIRIN

  • China Maxpharm Group null
  • Fax: 86-27-85788237 85787941
  • Address: B-24AB, Qingnian Plaza, Wuhan, 430022, China null,nullChina
Contact Supplier

36791-04-5 ribavirin

  • China innocechem-api [Manufacturers]
  • Tel: 18918206905
  • Address: shanghai null,nullChina
Contact Supplier

36791-04-5 ribavirin

  • China Yancheng Jingwei Chemicals Co., Ltd. [Manufacturers]
  • Tel: +86-(515)-8824-0043, 8823-7203
  • Fax: +86-(515)-8824-1811
  • Address: Room No.601-604, Building No.13, District A , Guofei Fashion Town, No.14 Middle Youth Road, Yancheng, Jiangsu 224001, Yancheng,JiangsuChina
Contact Supplier

36791-04-5 Ribavirin

  • China Taizhou Overseas Int'l Ltd. [Importer/Exporter]
  • Tel: +86-576-8881 2802
  • Fax: 86-576-88811658
  • Address: 126-8 QINGNIAN ROAD JIAOJIANG TAIZHOU ZHEJIANG CHINA Taizhou,ZhejiangChina
Contact Supplier

36791-04-5 Ribavirin

  • China N-Techem International Co.Ltd. null
  • Fax: 86-574-56707080
  • Address: Room 803, B Building, LiYuanShangDu, 39#, 158 Lane, HuanCheng XiLu, Ningbo, Zhejiang, China null,nullChina
Contact Supplier

36791-04-5 Ribavirin

  • China Suntin MediPharma Co. Ltd. [Importer/Exporter]
  • Tel: +86 755 8386 5062 ; +852 2690 9351
  • Fax: +86 755 8386 4173 ; +852 2690 9356
  • Address: RM.2501-2502, 25/F., Convention & Exhibition Times Center, 3008 Yitian RD., Shenzhen China. null,nullChina
Contact Supplier

36791-04-5 ribavirin

Contact Supplier

36791-04-5 ribavirin

  • China Zhuhai Yuancheng Pharmaceutical&chemical Co.,Ltd. [Distributor/Wholesaler]
  • Tel: +86-0756-8800236
  • Fax: +86-0756-8800230
  • Address: The gulf road No.227 gulf half of the bead arch in sea City north water mountain international apartment room 3101, Block 1 ZhuHai,GuangDongChina
Contact Supplier

36791-04-5 Ribavirin

Contact Supplier

36791-04-5 ribavirin

  • China Zhongbei Northland Bio-Chem Industry Co., Ltd [Manufacturer, Trading Company]
  • Tel: +86-452-6197129
  • Fax: +86-452-6197939
  • Address: 5F, C Liandalijing Bulding,No 259 Xinjiang Road, Jianhua District, Qiqiha''er,HeilongjiangChina
Contact Supplier

Select to

6/11
Previous 2 3 4 5 6 7 8 9 10 11 Next
References of Ribavirin
Title: Ribavirin
CAS Registry Number: 36791-04-5
CAS Name: 1-b-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
Synonyms: RTCA; tribavirin
Manufacturers' Codes: ICN-1229
Trademarks: Copegus (Roche); Rebetol (Schering-Plough); Viramid (Alfa); Virazide (Valeant); Virazole (Valeant)
Molecular Formula: C8H12N4O5
Molecular Weight: 244.20
Percent Composition: C 39.35%, H 4.95%, N 22.94%, O 32.76%
Literature References: Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Prepn: J. T. Witkowski, R. Robins, DE 2220246; eidem, US 3798209 (1972, 1974 both to ICN); J. T. Witkowski et al., J. Med. Chem. 15, 1150 (1972); eidem, J. Carbohydr. Nucleosides Nucleotides 5, 363 (1978). Regioselective synthesis: Y. Ito et al., Tetrahedron Lett. 1979, 2521. NMR study: G. P. Kreishman et al., J. Am. Chem. Soc. 94, 5894 (1972). Crystal structure: P. Prusiner, M. Sundaralingam, Nature New Biol. 244, 116 (1973). Teratogenicity study: D. M. Kochhar et al., Toxicol. Appl. Pharmacol. 52, 99 (1980). Review of antiviral activity: R. W. Sidwell et al., Pharmacol. Ther. 6, 123-146 (1979); of clinical experience: H. Fernandez et al., Eur. J. Epidemiol. 2, 1-14 (1986); of molecular modes of action: J. L. Patterson, R. Fernandez-Larsson, Rev. Infect. Dis. 12, 1139-1146 (1990). Clinical trial in infants with respiratory syncytial viral infection: C. B. Hall et al., N. Engl. J. Med. 308, 1443 (1983); in combination with interferon alfa-2b in hepatitis C: O. Reichard et al., Lancet 351, 83 (1998).
Properties: White to off-white powder. Freely sol in water; slightly sol in anhydrous alcohol. Exists in two polymorphic forms: mp 166-168° (aq ethanol); mp 174-176° (ethanol) (Witkowski, 1972). Also reported as mp 180-182° (Ito). [a]D25 -36.5° (c = 1 in water); [a]D20 -38° (c = 1 in water). LD50 i.p. in mice: 1.3 g/kg; orally in rats: 5.3 g/kg (Witkowski, 1972).
Melting point: mp 166-168° (aq ethanol); mp 174-176° (ethanol) (Witkowski, 1972); mp 180-182° (Ito)
Optical Rotation: [a]D25 -36.5° (c = 1 in water); [a]D20 -38° (c = 1 in water)
Toxicity data: LD50 i.p. in mice: 1.3 g/kg; orally in rats: 5.3 g/kg (Witkowski, 1972)
Therap-Cat: Antiviral.
Keywords: Antiviral; IMPDH Inhibitor.