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CAS No 38234-21-8 , Fertirelin

  • Name: Fertirelin
  • Synonyms: Luteinizing hormone releasing factor;Fertirelin;9-(N-Ethyl-L-prolinamide)-10-deglycinamide;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.49 g/cm3
  • Refractive index: 1.698
  • Flash Point: °C
  • Molecular Weight: 1153.29
  • InChI: InChI=1/C55H76N16O12/c1-4-59-53(82)44-12-8-20-71(44)54(83)38(11-7-19-60-55(56)57)66-49(78)39(21-30(2)3)65-46(75)27-62-47(76)40(22-31-13-15-34(73)16-14-31)67-52(81)43(28-72)70-50(79)41(23-32-25-61-36-10-6-5-9-35(32)36)68-51(80)42(24-33-26-58-29-63-33)69-48(77)37-17-18-45(74)64-37/h5-6,9-10,13-16,25-26,29-30,37-44,61,72-73H,4,7-8,11-12,17-24,27-28H2,1-3H3,(H,58,63)(H,59,82)(H,62,76)(H,64,74)(H,65,75)(H,66,78)(H,67,81)(H,68,80)(H,69,77)(H,70,79)(H4,56,57,60)/t37-,38-,39-,40-,41-,42-,43-,44-/m0/s1
  • Molecular Formula: C55H76N16O12
  • Molecular Structure:CAS No:38234-21-8 Fertirelin

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References of Fertirelin
Title: Fertirelin
CAS Registry Number: 38234-21-8
CAS Name: 9-(N-Ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine)
Synonyms: 9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing hormone-releasing factor (pig); Des-Gly10-NH2-LH-RH-ethylamide
Manufacturers' Codes: TAP-031
Molecular Formula: C55H76N16O12
Molecular Weight: 1153.29
Percent Composition: C 57.28%, H 6.64%, N 19.43%, O 16.65%
Literature References: Synthetic nonapeptide analog of LH-RH, q.v. Prepn: M. Fujino et al., DE 2321174; eidem, US 3853837 (1973, 1974 both to Takeda); S. Shinagawa, M. Fujino, Chem. Pharm. Bull. 23, 229 (1975); see also: M. Fujino et al., Biochem. Biophys. Res. Commun. 49, 863 (1972). Enzyme immunoassay in bovine plasma: J. Okada, S. Kondo, ibid. 33, 4464 (1985). HPLC determn of bulk drugs and formulations: P. A. Hartman, J. D. Stodola, J. Chromatogr. 444, 177 (1988). Field trial in bovine cystic ovarian disease: T. Nakao et al., Jpn. J. Vet. Sci. 45, 269 (1983); to induce ovulation for insemination of dairy cows: T. Nakao et al., Theriogenology 20, 111 (1983); K. Yamada et al., Anim. Reprod. Sci. 74, 27 (2002).
 
Derivative Type: Acetate
CAS Registry Number: 66002-66-2
Manufacturers' Codes: U-69689E
Trademarks: Conceral (Takeda); Ovalyse (Pharmacia & Upjohn)
Molecular Formula: C55H76N16O12.C2H4O2
Molecular Weight: 1213.34
Percent Composition: C 56.42%, H 6.65%, N 18.47%, O 18.46%
Properties: Pentahydrate as white, fluffy powder, [a]D25 -53.6° (c = 0.5 in 5% acetic acid).
Optical Rotation: [a]D25 -53.6° (c = 0.5 in 5% acetic acid)
 
Therap-Cat-Vet: Gonad stimulating principle.